RNA virus

related topics
{disease, patient, cell}
{acid, form, water}
{specie, animal, plant}
{group, member, jewish}
{math, number, function}

An RNA virus is a virus that has RNA (ribonucleic acid) as its genetic material.[1] This nucleic acid is usually single-stranded RNA (ssRNA) but may be double-stranded RNA (dsRNA).[2] The ICTV classifies RNA viruses as those that belong to Group III, Group IV or Group V of the Baltimore classification system of classifying viruses, and does not consider viruses with DNA intermediates as RNA viruses.[3] Notable human diseases caused by RNA viruses include SARS, influenza and hepatitis C.

Another term for RNA viruses that explicitly excludes retroviruses is ribovirus.[4]

Contents

Characteristics

Single-stranded RNA viruses and RNA Sense

RNA viruses can be further classified according to the sense or polarity of their RNA into negative-sense and positive-sense, or ambisense RNA viruses. Positive-sense viral RNA is similar to mRNA and thus can be immediately translated by the host cell. Negative-sense viral RNA is complementary to mRNA and thus must be converted to positive-sense RNA by an RNA polymerase before translation. As such, purified RNA of a positive-sense virus can directly cause infection though it may be less infectious than the whole virus particle. Purified RNA of a negative-sense virus is not infectious by itself as it needs to be transcribed into positive-sense RNA, however each virion can be transcribed to several positive-sense RNAs. Ambisense RNA viruses resemble negative-sense RNA viruses, except they also translate genes from the positive strand.[5]

Full article ▸

related documents
Toxicology
Fibronectin
Tyrosine kinase
Galactose
Acetylcholine receptor
General anaesthetic
Beta-lactamase
Ketone bodies
Stop codon
Nicotinamide
Casein
Colloidal silver
Alpha-linolenic acid
Antiseptic
Clinical chemistry
Perspiration
Adrenocorticotropic hormone
Hemoglobinopathy
Electrology
Integrase
Camillo Golgi
Ileum
Xanthine oxidase
Clostridium botulinum
Urea breath test
Mold
Arginine
Trimethoprim
Bioaccumulation
Proteinuria