The size of a typical eukaryotic cell is usually of the order of ~10 μm. However, some cell types grow to very large sizes, up to 1 mm. Graduate student Marina Feric in the Brangwynne lab has used microrheology and quantitative imaging to show that large nuclei contain an elastic F-actin scaffold that mechanically stabilizes them against gravitational forces.
Grad student Mikhail Maksimov *15 and Professor Jamie Link have isolated and characterized an enzyme, lasso peptide isopeptidase, that “unties” the lasso structure. This enzyme suggests additional layers of regulation or perhaps new functions for lasso peptides.
Professor Jamie Link and grad student Frank Piscotta, in collaboration with the Liu group at Texas A&M, have provided the first demonstration that unnatural amino acids can be introduced into the antimicrobial lasso peptide microcin J25. Four different amino acids were tolerated at four different positions, and all 16 of these variants retained antimicrobial activity.
Mapping the Crystalline Phase Space of a Molecular Semiconductor to Understand Effects on Charge Transport
Small molecules – be they pharmaceuticals, explosives, dyes, flavors for food, or, as the Loo Group studies, molecular semiconductors – can adopt a variety of crystal structures, a phenomenon known as polymorphism.
Alexander Holiday, a third-year PhD student in the group of Professor Yannis Kevrekidis has won a poster presentation prize at the "Advances in Discrete Networks” international workshop hosted by U. of Pittsburgh's Dept. of Mathematics from Dec. 12-14, 2014. His presentation was entitled "Coarse graining of a dynamically evolving network.”
Carmeline Dsilva, a fifth-year PhD student in the group of Professor Yannis Kevrekidis has won the 2014 CAST Directors’ Student Presentation Award from the Computing and Systems Technology Division of the American Institute of Chemical Engineers. The award was given for Carmeline’s talk at the Annual AIChE meeting in Atlanta on "Data-Driven Methods for the Analysis of Multiscale Stochastic Systems,” in which she discussed dimensionality-reduction techni
Two fourth-year CBE doctoral students have been awarded 2014-15 Honorific Fellowships by the Princeton University Graduate School, which will provide full tuition and stipend for their fifth and final year of Ph.D. study. Kimberly Shepard, who is working with Professors Rodney Priestley and Craig Arnold (MAE), will receive a Porter Ogden Jacobus Fellowship, while George Khoury, who is working with Professor Christodoulos Floudas, will receive a Wallace Memorial Fellowship in Engineering.&n
Earlier today, first-year Chemical and Biological Engineering Ph.D. student Andrew Santos was awarded a three-year National Science Foundation Graduate Research Fellowship in support of his research here at Princeton. Santos is working with Professor Athanassios Panagiotopoulos on “Self-Assembly of Ionic Surfactants and Block Copolymers in Solution”. Congratulations, Andrew!
At the Ninth Annual Innovation Forum, held February 26, CBE teams took both the First and Second Prizes. Vikram Pansare GS5, representing a team including his advisor, Professor Robert Prud’homme, as well as fellow CBE Ph.D. students Chuan Zhang GS5 and Chris Sosa GS3, and Professor Rodney Priestley, took First Prize (and $15,000 in flexible research funding) for a technology for mass production of “Janus particles,” tiny spheres with two distinct sides composed of typica
At a lunch and ceremony today, open to the entire School of Engineering and Applied Science, the Princeton Engineering Council (E-Council) and Graduate Engineering Council (GEC) jointly recognized faculty and graduate students for excellence in teaching during calendar 2013. CBE Ph.D. student David (DJ) Bozym was honored with the sole Assistant in Instruction (AI) award for Spring 2013, for his work in the junior-level CBE 346, “Chemical Engineering Laboratory”. Recipient
At the 2013 Princeton Research Symposium (PRS), held on October 20 on campus, fourth-year CBE Ph.D. student George Khoury was awarded 1st Prize in the Poster Competition, and 2nd prize in the Oral Research Talks. PRS is an annual interdisciplinary event, first launched in 2006, where Princeton graduate students and post-doctoral researchers present a diverse body of work to the University community, alumni, and general public. George's thesis work, advised by Professor Christodou
CBE doctoral student Marina Feric, and her advisor, CBE Assistant Professor Clifford P. Brangwynne, have discovered that gravity can play an important role in cells. Feric and Brangwynne set out to understand how liquid-like RNA/protein (RNP) organelles are stabilized within the nucleus of large frog cells. By using small probe particles to make micro-rheological measurements in the cell nucleus, they found that an actin biopolymer scaffold constrains the motion of RNP droplets. Unex
At the 12th International Conference on Laser Ablation (COLA 2013), held last week in Ischia, Italy, fourth-year CBE Ph.D. student Kimberly Shepard was recognized with an Outstanding Presentation Award, consisting of a certificate and 150 Euro. Kim's thesis work, advised by Professor Rodney Priestley, focuses on the use of Matrix Assisted Pulsed Laser Evaporation to deposit amorphous polymer films with unique properties. Congratulations, Kim!
First-year CBE Ph.D. student Logan Matthews recently received First Prize in the 2013 American Institute of Chemical Engineers (AIChE) Student Design Competition (Individual Category), for work done during his senior year at Michigan State University. Each year, practicing chemical engineers from a designated company devise and judge a student contest problem that typifies a real, working, chemical engineering design situation. The problem’s solution requires a wide range of skills i
The American Society for Engineering Education recently announced the recipients of the National Defense Science and Engineering Graduate (NDSEG) Fellowships for 2013, including Princeton CBE Ph.D. students Geoffrey Purdum and Michael Howard. Purdum, a first-year graduate student, is working with Professor Lynn Loo for his dissertation research, while Howard will be starting his Ph.D. studies at Princeton this Fall. The three-year NDSEG awards cover the recipients’ tuition and
A research innovation for cost-effective carbon capture technology, developed by fourth-year Ph.D. student Eric First, Postdoctoral Associate Faruque Hasan, and Professor Christodoulos Floudas, has been selected as a finalist in the Future Energy competition, from over 100 qualified applicants. Future Energy is an energy and clean technology pitch event focused on the development and commercialization of radical solutions to the world's energy challenges. The First-Hasan-Floudas invent
Two CBE graduate students have been awarded Honorific Fellowships by the Princeton University Graduate School for the 2013-14 academic year, which will provide full tuition and stipend for their fifth and final year of Ph.D. study. Talal Al-Housseiny, who is working with Professor Howard Stone, will receive a Wallace Memorial Fellowship in Engineering, while Mikhail Maksimov, who is working with Professor Jamie Link, will receive a Harold W. Dodds Fellowship. A total of 20-30 Honorif
First-year Chemical and Biological Engineering Ph.D. students Granton Jindal and Michael Siedlik were recently each awarded a three-year National Science Foundation Graduate Research Fellowship in support of their research here at Princeton. Jindal is working with Professor Stanislav Shvartman on “Live Imaging and Computational Modeling of Heart Development”, while Siedlik is working with Professor Celeste Nelson on “Building a Designer Lung”. CBE alumnus Thom
Fourth-year Ph.D. student Eric First, representing a team including his advisor, Professor Christodoulos Floudas, and Postdoctoral Associate Faruque Hasan, took home Second Place (and $10,000 in flexible research funding) at Princeton’s 8th Annual Innovation Forum, held on March 12. Sponsored by the Keller Center for Innovation in Engineering Education, the purpose of the Innovation Forum is to showcase Princeton research that offers the potential to be commercialized. First&rs
At a lunch and ceremony on February 22, open to the entire School of Engineering and Applied Science, the Princeton Engineering Council (E-Council) and Graduate Engineering Council (GEC) jointly recognized a record-breaking FOUR members of the CBE department for their excellence in teaching during Fall 2012. Professor Yannis Kevrekidis was recognized for his teaching in the graduate-level course CBE 502, “Mathematical Methods of Engineering Analysis II”. Professor Pablo D
Research from the group of Christodoulos Floudas, Stephen C. Macaleer ’63 Professor of Engineering and Applied Science, has demonstrated a path to the U.S. production of synthetic fuels by the Fischer-Tropsch process at costs comparable to current crude oil prices, and with a net reduction in CO2 emissions of as much as 50%. The key is an optimally-distributed network of plants sited throughout the U.S., with the use of switchgrass (in conjunction with coal and natural gas) to achiev
Ruth Misener, a fifth-year CBE Ph.D. student working with Professor Christodoulos Floudas, has been awarded a 2012 Research Fellowship from the United Kingdom’s Royal Academy of Engineering. This postdoctoral fellowship will fund Ruth and her associated research costs for five years after her graduation from Princeton. Ruth will be based in the Department of Chemical Engineering at Imperial College London, developing a hybrid computational/experimental approach towards personal
Fourth-year CBE Ph.D. student Josephine Elia has been selected by the Andlinger Center for Energy and the Environment (ACEE) to receive the inaugural Maeder Graduate Fellowship in Energy and the Environment for the coming academic year, 2012-2013. Josephine is working with Professor Christodoulos Floudas on the computational discovery and operation of hybrid energy processes, whereby a broad range of raw resources (coal, biomass, and natural gas) can be converted to an optimal mix of
This semester will be doubly memorable for William Holloway *12: after successfully defending his Ph.D. thesis on April 24, he was notified yesterday that he has been selected as one of six recipients of a 2012 APGA Teaching Award from the Association of Princeton Graduate Alumni. Holloway was recognized for his exceptional service as an Assistant in Instruction (AI) for CBE 246, “Thermodynamics”, taught by Professor Athanassios Panagiotopoulos in Spring 2011. The a
Fourth-year Chemical and Biological Engineering Ph.D. student Karthikeyan Rajendran has been named as one of three 2012 recipients of the Ray Grimm Memorial Prize. Rajendran, who is working with Professor Yannis Kevrekidis, was recognized with the $4,000 prize, “for his ingenious and innovative combination of modeling and scientific computing tools, from nonlinear dynamics, multiscale modeling, optimization and uncertainty quantification with ideas from graph theory towards the model
First-year Chemical and Biological Engineering Ph.D. student Anna Hailey was today awarded a three-year National Science Foundation (NSF) Graduate Research Fellowship in support of her research here at Princeton. Hailey is working with Professor Lynn Loo on “Controlling Crystallization in Solution-Processed Binary Blends for Organic Photovoltaics”. CBE alumnus Jeff Thompson ’10, currently a graduate student at the University of Texas at Austin, was also selected for
At a lunch and ceremony on February 21, open to the entire School of Engineering and Applied Science, the Princeton Engineering Council (E-Council) and Graduate Engineering Council (GEC) jointly recognized two members of the CBE department for their excellence in teaching during Spring/Fall 2011. Professor Sankaran Sundaresan received the sole Spring 2011 faculty award, for his teaching in the graduate-level course CBE 505, “Advanced Heat and Mass Transfer”. George Khoury
This Saturday, February 25, both a CBE alumna and a current CBE graduate student will be recognized by the University at Alumni Day with two of its top honors. Lisa P. Jackson, Administrator of the U.S. Environmental Protection Agency, will receive the Madison Medal, presented each year to an alumnus or alumna of the Graduate School who has had a distinguished career, advanced the cause of graduate education or achieved an outstanding record of public service. Jackson received her M.