CBE Ph.D. student Jonathan Robinson G5 has been named one of three Emerging Alumni Scholars for 2015 by the Alumni Council's Committee on Academic Programs for Alumni. Robinson’s work on “Exploration of Bacterial Nitric Oxide Stress Responses as a Source of Antivirulence Targets”, advised by Professor Mark Brynildsen, was selected to showcase, and to share with Princeton alumni, some of the best doctoral research being conducted at the University. Robinson&rsquo
Mark Brynildsen, Assistant Professor of Chemical and Biological Engineering, has been awarded a Faculty Early Career Development (CAREER) Award from the National Science Foundation (NSF). Brynildsen’s project, entitled “Metabolic Engineering to Potentiate Immunity and Discover Novel Antivirulence Therapies”, will focus on developing antivirulence therapies as a novel class of anti-infectives and an alternative to antibiotics, to which organisms have shown steadily increas
Prof. Brynildsen is a recipient of an NSF CAREER award that focuses on studying nitric oxide stress in bacteria with approaches adopted from metabolic engineering to discover novel antivirulence therapies. Depicted above, a simplified diagram of the Escherichia coli nitric oxide response network.
Recent research by a team at Boston University spearheaded by Mark Brynildsen, now Assistant Professor of Chemical and Biological Engineering at Princeton, has shown how bacteria can be forced to increase their production of reactive oxygen species (ROS)—either killing the bacteria outright, or making them vulnerable to antibiotics at lower dosages. By developing genome-scale metabolic models describing the production of reactive oxygen species in the bacterium E. coli, and then pert
The January 18 issue of the Princeton Alumni Weekly, mailed to all Princeton alumni, carried as an insert the Winter 2012 issue of the EQuad News, dedicated to “Exploring the Intersection between Engineering and Health”, in which several CBE faculty members were prominently featured. An article on “Designing New Biological Molecules to Fight Bacteria and Cancer” described the experimental work in the group of Assistant Professor A. James Link on designing antimicrob
Last week, first-year Chemical and Biological Engineering Ph.D. students Nathan Mahynski and Jonathan Robinson were awarded National Science Foundation (NSF) Graduate Research Fellowships in support of their research here. Mahynski is working with Professor Thanos Panagiotopoulos on “Self-Assembly of Polymer-Grafted Nanoparticles”, while Robinson is working with Professor Mark Brynildsen on “Improving Killing of Bacteria by Reactive Nitrogen Species”. Heartiest congratula
Mark P. Brynildsen and Clifford P. Brangwynne will join the Department of Chemical and Biological Engineering as Assistant Professors during the coming academic year. Each will expand and strengthen the department’s research portfolio in biological engineering. Brynildsen, who will start in September 2010 following a postdoctoral appointment in Biomedical Engineering at Boston University, specializes in host-pathogen interactions, bacterial persistence, and biofilms. Brangwynne, who will