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Jared Toettcher

Selected Publications

  1. Toettcher JE, Weiner OD, Lim WA. (2013) Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module. Cell 155: 1422-34. Pubmed
  2. Toettcher JE, Gong D, Lim WA, Weiner OD. (2011) Light-based feedback for controlling intracellular signaling dynamics. Nat Methods. 8: 837-839. Pubmed
  3. Toettcher JE, Voigt CA, Weiner OD, Lim WA. (2011) The promise of optogenetics in cell biology: interrogating molecular circuits in space and time. Nat Methods. 1: 35-38. Pubmed
  4. Toettcher JE, Gong D, Lim WA, Weiner OD. (2011) Light control of plasma membrane recruitment using the Phy-PIF system. Methods Enzymol. 497: 409-23. Pubmed
  5. Toettcher JE, Castillo A, Tidor B, White JK. (2011) Oscillator sensitivity analysis in the presence of hidden conservation constraints. Proceedings of the 48th IEEE Design Automation Conference 806-811.
  6. Toettcher JE, Apgar JF, Castillo AR, Tidor B, White JK. (2011) Recycling circuit simulation techniques for mass-action biochemical kinetics. Advanced Simulation and Verification of Electronic and Biological Systems, 115-136.
  7. Toettcher JE, Mock C, Batchelor E, Loewer A, Lahav G. (2010) A synthetic-natural hybrid oscillator in human cells. Proc Natl Acad Sci. 107: 17047-52. Pubmed
  8. Toettcher JE, Loewer A, Ostheimer GJ, Yaffe MB, Tidor B, Lahav G. (2009) Distinct mechanisms act in concert to mediate cell cycle arrest. Proc Natl Acad Sci. 106: 785-90. Pubmed
  9. Apgar JF, Toettcher JE, Endy D, White FM, Tidor B. (2008) Stimulus design for model selection and validation in cell signaling. PLoS Comput Biol. 4: e30. Pubmed
  10. Weinberger LS, Burnett JC, Toettcher JE, Arkin AP, Schaffer DV. (2005) Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity. Cell 122: 169-82. Pubmed