Welcome to the Brangwynne lab at Princeton University. We are an interdisciplinary team of engineers, biologists, and physicists using principles of soft matter physics to understand the structure and self-assembly of living biological materials, including the cytoskeleton, organelles, cells, and tissues.
We are currently recruiting people to our team! If you are enthusiastic and have a drive to use cutting edge techniques spanning multiple disciplines, are fearless in asking and tackling fundamental questions about how nature works, then you should join us!
4/19/16 - Congratulations to the soon-to-be Dr. Marina Feric, the first PhD minted in the Brangwynne lab! Marina successfully defended her fantastic thesis and then the lab went out and celebrated with good food and some pool, and topped it off with ice cream and waffles from Ninas.
4/18/16 - Cliff back from a great little meeting at the McGill research facility in Barbados. Thanks to Jackie Vogel, Simon Alberti, and Mathieu Blanchette for organizing, especially for having it in such a fantastic location (yes, next time I'll try to bring other lab members!)
4/2/16 - Cliff back from giving a seminar at the University of Wyoming. Thanks to Dan Levy for organizing a great visit to a fun place.
3/18/16 - Cliff back from giving a seminar at the University of Chicago, in the Department of Molecular Genetics and Cell Biology. Thanks to Will Yee and the other PhD students for the invitation to their Student-Invited Seminar Series!
3/2/16 - Shani and Nicole are back from the Biophysical Society meeting in LA. Shani gave a talk and picked up her Molecular Kinetics Postdoctoral Research Award, and Nicole gave a talk about her work using microfluidics to study RNA/protein liquids (her first big talk went very well!).
3/1/16 - Welcome to our visitor Saskia Lindhoud from University of Twente in the Netherlands, who is spending the week here interacting with our group.
2/24/16 - Cliff back from giving a seminar in the Biomedical Engineering department at Carnegie Mellon University. Thanks to Adam Feinberg for being a great host. This was a particularly nice visit since Cliff hasn't been at CMU since graduating in 2001 (this slide got some good laughs!).
2/13/16 - Cliff back from giving a course lecture and institute seminar at the Instituto Gulbenkian in Portugal. Thanks to Monica Bettencourt Dias and Florence Janody for hosting a wonderful visit.
2.5.16 - Shani wins the prestigious and highly competitive K99 award from the NIH! Way to go Shani!!!!
1/29/16 - Cliff back from giving a talk at the Mid-Atlantic Soft Matter meeting (MASM16), which was held at the NIH in Bethesda, Maryland. Thanks to Dan Blair and Kandice Tanner for organizing a great meeting.
1/14/16 - Cliff back from a great meeting in Japan, organized by the Japanese society for quantitative biology. The meeting was held at the University of Tokyo and the National Institute of Genetics in Mishima - a smaller city with great views of Mt. Fuji. Thanks to the organizers, especially Aki Kimura (as well as former Tokyo resident and Princeton CBE alum Keisuke Ishihara), for being outstanding hosts and making this a very special meeting (among other treats, including out-of-this-world Sushi!).
1/1/16 - Congratulations to Shani who has been selected as a recipient of a Molecular Kinetics Postdoctoral Research Award from the Biophysical Society. Way to go Shani!
12/29/15 - Our work takes center stage in this article on Princeton's growing Bioengineering program.
12/16/15 - The Brangwynne lab was well-represented at the 2015 ASCB meeting in San Diego. The session organized by Cliff, Gary Brouhard, and Xiolei Su was a success, including a great talk by Steph. Shani and Marina also gave great talks at other sessions, and Nicole had a poster. Cliff also picked up his ASCB-Gibco prize. (See pic from our nice dinner at the meeting)
12/10/15 - 4th annual lab holiday party was great. This year's secret santa hit was a "shot glass roulette wheel".
12/7/15 - Cliff back from giving a talk in the Biochemistry department at the University of Montreal. Thanks to Steve Michnick for hosting a nice visit (a great group of folks in a great town where Steph is launching her own lab @McGill !)
12/4/15 - Thanks to Jim Ferrell and the other members of the Stanford Center for Systems Biology for hosting a great symposium with talks by Cliff, Ron Weiss, Dana Pe'er, and Philippe Bastiaens.
11/27/15 - New lab tradition for "Black Friday": select Brangwynne lab members up very early to get the best deals on Chai latte and science!
11/20/15 - The Brangwynne lab says goodbye to postdocs Sravanti Uppaluri and Shashi Thutupalli, who are off to faculty positions in India. We had a nice going away dinner and presented them with a beautiful piece of Chinese artwork to decorate their new home.
11/5/15 - Cliff back from a great seminar visit to National University of Singapore. Thanks to Greg Jedd for the wonderful science and conversation (highlights: wild King Cobra sighting, and great food especially Xiao Long Bao).
10/30/15 - The Brangwynne lab participated in a fantastic webinar on phase transitions in cells, sponsored Alzforum. Cliff gave a talk, joined by Paul Taylor, Nick Fawzi, Simon Alberti, Peter St. George-Hyslop, and Markus Zweckstetter. Thanks to Amber Dance for organizing.
10/30/15 - Rapidly growing interest in phase transitions in the neurodegeneration community. See this report (with quotes from Cliff).
10/29/15 - Cliff back from giving a talk at the NIH for the kickoff meeting for our recent grant with the 4D Nucleome Consortium. It's going to be very exciting over the next few years to see the discoveries that come through this program.
10/26/15 - Cliff back from giving a seminar in the Molecular Structure and Function program at the Hospital for Sick Children in Toronto. Thanks to Julie Forman-Kay for hosting a great visit (including great conversation about music and phase transitions over Sushi).
10/21/15 - Cliff back from giving a seminar in the Biomedical Engineering department at WashU in St. Louis. Thanks to Rohit Pappu for hosting a great visit!
10/16/15 - It's raining RNA/protein liquids!
10/4/15 - Cliff back from giving a talk at the University of Chicago polyelectrolyte meeting. Thanks to Matt Tirrell, Juan de Pablo, and the other organizers for a great meeting!
9/26/15 - Brangwynne Lab back from our third annual retreat. This time we went to the Jersey Shore! Thanks to Shani and Lian for organizing another really great retreat!
9/18/15 - Cliff wins ASCB-Gibco Emerging Leader prize!
9/18/15 - Cliff back from giving a lecture in the Physics department at NYU. Thanks to Alexandra Zidovska for being a great host.
9/9/15 - Cliff back from giving a joint seminar in the Chemical Engineering and Physics departments at UMass Amherst. Thanks to Maria Kilfoil, Jenny Ross, Shelly Payton, and the other great hosts.
9/5/15 - Cliff gets a bunch of quotes in this nice article on the ALS forum website.
9/4/15 - Cliff back from giving a seminar in the Biomedical Engineering Department at UT Austin. Thanks to Amy Brock and colleagues for a nice visit!
9/2/15 - Welcome to Laura Gray, our new postdoc working jointly with the Priestley lab.
9/2/15 - The Brangwynne lab awarded a grant from the NIH as part of the 4D Nucleome Program to study phase transition-driven nuclear body assembly. Congrats!
8/21/15 - Cliff back from giving a talk at the CECAM IDP meeting in Zurich. The IDP field is getting very excited about phase transitions!
8/14/15 - Cliff back from another great Soft Matter Gordon Conference in NH. See you all again at the next one in two years!
8/6/15 - Steph, Joel, and Nilesh's paper accepted at PNAS! A nice combination of experiment and theory resulting from a fantastic collaboration with the Haataja group. Way to go!
7/31/15 - Welcome to Aleena Patel, a first year CBE PhD student who is doing a mini-rotation in the lab.
7/9/15 - The Brangwynne lab says goodbye to our beloved postdoc Steph Weber who is off to a faculty position - she will be starting her independent research career at McGill University. Best of luck Steph!
6/29/15 - Cliff back from giving a talk at the Developmental Biology Gordon Conference. Thanks to Susan Mango and the other organizers for a great meeting.
6/6/15 - Cliff back from giving a talk at the Macromolecular Assemblies meeting in Jerusalem. Thanks to Daniel Kaganovich and the other organizers for hosting a great meeting in an incredibly interesting location!
5/14/15 - Cliff part of a team consisting of Sabine Petry (Princeton Molecular Biology Dept.) and Simone Reber (Humboldt University, Berlin) awarded a Princeton-Humboldt Strategic Partnership grant to pursue an international collaboration to study membrane-less organelles.
4/26/15 - Cliff back from giving a seminar at Harvard as part of the Engineering and Physical Biology (EPB) Symposium. Thanks to Nancy Kleckner for organizing a great session among old friends!
4/22/15 - Our Intracellular Phase Transition Meeting was a success. Thanks to Ned and Mikko for helping co-organize, and to Charlene Borsack and the PCTS for being amazing with the logistics. Congrats also to all the Brangwynne labbers who gave posters, and to Shani, Steph and Joel for giving great talks!
3/31/15 - Congratulations to both Lian and Nicole for winning prestigious NSF Graduate Fellowships! Way to go!!!
3/21/15 - Cliff back from giving a seminar at UCSD. Thanks to Jim Wilhelm, Arshad Desai, Karen Oegema and co. for a great visit.
3/9/15 - William and Sravanti's paper on worm mechanics is accepted at Biophysical Journal! What great senior thesis work William!
3/4/15 - Cliff back from giving a talk at a great meeting at the Cold Spring Harbor Lab on Cellular Dynamics and Models.
2/20/15 - Steph's paper on inverse size scaling of the nucleolus is published in Current Biology! Way to go Steph!!!
2/17/15 - Cliff back from giving a seminar in the Chemistry department at Penn State. Thanks to Christine Keating for being a great host.
2/10/15 - Shani and Cliff back from the 2015 Biophysical Society Annual meeting in Baltimore. Cliff gave a talk at the Intrinsically Disordered Subgroup session, and Shani presented a (very popular!) poster.
1/31/15 - Cliff back from giving the Danny Thomas Lecture at St. Jude. Thanks to Paul Taylor and Richard Kriwacki for being great hosts! (cool pic flying back into Philly).
1/20/15 - Cliff back from giving a seminar at Georgetown Physics. Thanks to Rhonda Dzakpasu for hosting (and helping find Cliff's keys!).
1/2/15 - Congrats to Lian Zhu for passing her first prop! That makes three for three this year, way to go!
1/7/15 - Sara Chuang featured on AIChe website!
12/18/14 - 3rd annual Brangwynne lab holiday party was wonderful -- thanks to everyone for coming and contributing to the yummy potluck feast (this year people were actually somewhat civilized during the Secret Santa gift exchange!).
12/11/14 - Sravanti and Cliff back from another rewarding outreach visit to Kilmer Elementary School in Trenton. Thanks again to Mrs. Millner, our favorite 8th grade teacher in New Jersey!
12/10/14 - Brangwynne lab members Steph, Sravanti, Sara, Marina, Shani and Cliff are back from the 2014 ASCB Annual Meeting in Philadelphia after giving several talks and posters. Congrats to everyone for a job well done!
11/19/20 - Cliff and Sara back from AIChe meeting in Atlanta. Cliff chaired a Cellular Biomechanics session and gave a talk, and Sara served as a mentor for undergraduates at the meeting.
10/31/14 - Cliff heading back from giving a seminar at Imperial College London [actually two seminars: the fire alarm went off halfway through the seminar, so the second half ended up being rescheduled for later that afternoon!]. Thanks to Chiu Fan Lee and James Choi for being excellent hosts.
10/18/14 - Brangwynne Lab back from the 2nd Annual Lab Retreat! We returned to the Poconos this year and had a great time discussing science, hiking, and eating!
10/7/14 - 4th HFSP Team Helicase Retreat was a success! Thanks to Christian, Sua, Krzysztof, and Younghoon for coming to Princeton for another great gathering. (Dinner Pic)
9/22/14 - Cliff back from giving a talk at the Physics of Living Matter 9 Meeting in Cambridge, UK.
9/10/14 - CBE 433/533, Introduction to Soft Living Matter has its first class of the semester. Cliff is teaching, Marina is the teaching assistant (AI), and Lian, Nicole, Sara, Kevin, and Bruna are taking it! Have fun everybody!
8/29/14 - Cliff back from giving a talk at the Xenopus meeting in Pacific Grove. Thanks to John Wallingford and the other froggers for a great meeting.
8/25/14 - Nicole is clean-room initiated!
8/19/14 - 3rd Annual Brangwynne Lab end-of-summer party is a success! (new tradition: backyard frisbee)
7/22/14 - Marina gives a talk on her work at the International Physics of Living Systems (iPoLS) meeting in Munich Germany.
7/14/14 - Steph gives a talk on her work at the Post-Transcriptional Gene Regulation Gordon Conference in Newport, RI
7/9/14 - Cliff gives a talk at the Intrinsically-Disordered Protein Gordon Conference at Stonehill College, MA
6/16/14 - Four members of the Brangwynne lab are spending 7 weeks at the Marine Biological Laboratory (MBL) in Woods Hole, MA. Lian will be a student in the famous Physiology course, which involves intensive hands-on research training in cutting edge quantitative techniques. Sara, Nilesh and Cliff (see "action photo" of an experiment with yeast!) are doing research as part of an HHMI-funded Summer Institute focused dissecting the biophysical rules governing RNA/Protein assembly.
5/27/14 - Cliff back from giving a seminar at UCSF - thanks to Dyche Mullins for being a great host.
5/2/14 - Cliff part of a team awarded funding through the Eric and Wendy Schmidt Transformative Technology Fund. The team includes Prof. Rick Register (CBE), Prof. Rod Priestley (CBE) and Prof. Craig Arnold (MAE). The team will develop a novel 3D Nanorheometer technology for studying material properties at the nanoscale, including the properties of liquid-phase RNA/Protein organelles.
4/30/14 - Shani and Cliff back from another great outreach visit to Kilmer Elementary School in Trenton. The students were excited to hear about some of the advantages of careers in STEM, and learn about our lab's work on phase transitions in cells.
4/22/14 - Cliff awarded the Wentz Junior Faculty Award!
4/9/14 - Cliff back from his second Searle Scholars meeting in Chicago. Great to see old and new friends, and play with some of the exhibits especially the impact crater simulation, during the reception at the Adler Planetarium.
3/19/14 - Cliff back from giving a seminar at Penn CBE. Thanks especially to Dennis Discher, John Crocker, and Daeyeon Lee for being great hosts!
3/5/14 - Cliff back from the APS March meeting in Denver. Some great sessions on biological phase transitions!
2/18/14 - Cliff wins Sloan Award!
2/10/14 - Congrats to undergrad William Gilpin for being accepted into many fantastic Ph.D. programs including Harvard, Stanford, and Yale.
1/6/13 - The Brangwynne lab welcomes 1st year CBE Ph.D. students Sara Chuang, Nicole Taylor, and Lian Zhu!
12/19/13 - Brangwynne lab members back from a fantastic 2013 ASCB meeting in New Orleans. Highlights include a great talk by Marina in Cliff's Physics of the Nucleus Session, Posters by Steph, Sravanti and Marina, and the first ever ASCB Brangwynne lab dinner. Looking forward to next year in Philadelphia!
12/5/13 - Thanks to everyone for coming to the second annual Brangwynne Lab Holiday Party - yummy food, desserts, drinks, and Secret Santa (Cliff scores "Cube Robot").
11/3/13 - Congratulations to Nilesh for winning a highly prestigious Helen Hay Whitney Fellowship!! Must've been the Shoes!!
10/21/13 - Shani, Nilesh, and Cliff are back from a fantastic meeting of HFSP Team Helicase, UIUC 2013! Thanks to Sua Myong and Younghoon Kim for organizing another great gathering!
10/12/13 - Brangwynne lab Retreat 2013 was awesome!
10/2/13 - Cliff back from a nice meeting in Goettingen Germany on "Physics of the Embryo"
10/1/13 - Marina's Gravity paper finally published in Oct. 1 issue of Nature Cell Biology
9/25/13 - Cliff back from giving a seminar at Dartmouth. Thanks especially to Jamie Moseley, Erik Griffin, and Amy Gladfelter for being great hosts!
9/6/13 - The first monthly BioEngineering Colloquium in Hoyt was great!
9/4/13 - Annual end of summer lab party at Cliff's house was a success (highlight was Sravanti's compliment of Cliff's homebrew: "Not disgusting, even tastes kind of like beer!")
8/22/13 - Soft Matter Gordon Conference was fantastic. We're looking forward to the next one two years from now!
7/2/13 - Congrats to Cliff on "recruiting" the newest lab member (out of the womb!)
6/4/13 - Congratulations to Brangwynne lab alumni Max Jacobson, Nikhil Chervu, Jeff Wang, and the other members of the Class of 2013!
5/10/13 - Congrats to rotation student Jamie Barr and undergrad William Gilpin, whose pictures were selected for inclusion in the 2013 Princeton Art of Science Exhibition!!
4/27/13 - Congrats to athletes including Shani, Marina, Cliff, Victor, and the winner Steph, who participated in another Princeton Athletic Club 6k run through the IAS woods! (group photo).
4/23/13 - Cliff back from Searle Scholars meeting in Chicago (received a very nice commemorative plaque). Science, Picassos, great food, and a fantastic group of very interesting people!
4/12/13 - Graduate student Marina Feric gave a great talk at the Developmental Colloquium on her work with Xenopus oocyte nuclei. Congrats on a job well done!
3/25/13 - Cliff back from giving an invited talk at the APS March Meeting in a session on "Active, Nonequilibrium dynamics in complex cellular networks" (Session Z47.... the very last one on Friday!).
2/27/13 - The Brangwynne lab has just completed a quick and surprisingly (nearly) painless move to its new and improved location in the Hoyt Laboratory! Come by and visit us!
2/6/13 - Cliff gave a lecture for ELE547C entitled "The Biophysics of Cell Growth: Building Organisms of Just the Right Size". Thanks to Prof. Sigurd Wagner for organizing a great Graduate Seminar Course.
2/6/13 - The Brangwynne lab back from the Biophysical Society Meeting in Philadelphia - congrats to Steph, Sravanti, and Marina for presenting posters. Thanks to the organizers of the symposium on "Mechanics in the Nucleus" (Lab members report that Cliff gave a good talk even though the infamous "Hoff" slide was not included).
12/20/12 - Cliff back from a great ASCB meeting in San Francisco. Thanks to RNA minisymposium co-chair Tracy Johnson and the other speakers for a terrific session!
12/1/12 - Congrats to the hearty Brangwynne lab athletes who successfully ran the 6k Winter Wonder Run through the IAS Woods this Saturday!
11/30/12 - Cliff and Sravanti spent the morning with 8th grade students at Kilmer Elementary School in Trenton, sharing the excitement of science, microfluidics, and worm biology. Thanks to Mrs. Millner and her great class!
11/3/12 - The Brangwynne lab has survived superstorm Sandy! Cliff's house power is back after 4 candlelit and chilly nights; hopefully everybody else is soon back too. Thanks to Shani for opening up her home to the bedraggled!
9/25/12 - The Brangwynne lab welcomes a crop of newbies including Senior Thesis Students Max Jacobson and Nikhil Chervu and rotation students Jack Lu and Jamie Barr. Also welcome back to undergraduates Jeff Wang and William Gilpin.
9/14/12 - Cliff wins NIH New Innovator Award!
8/23/12 - The first annual Brangwynne lab (end-of)Summer Pizza Party was a success!
6/15/12 - Cliff back from giving a talk at a conference on Molecular Crowding at Monte Verita in Switzerland. Thanks to Guiseppe Foffi for organizing a great meeting!
6/4/12 - Congrats to Axel Shum for winning the Ticona Award for Outstanding Senior Thesis for his work on nucleoli in the Brangwynne lab!
5/17/12 - Postdoc Steph Weber is awarded a highly prestigious fellowship from the Damon Runyon Cancer Research Foundation! Congratulations Steph!
5/10/12 - Cliff back from giving a seminar at Queens College (CUNY) - what a fun and highly interactive audience.
5/8/12 - Thanks to Christian Eckmann and Sua Myong for a great kickoff meeting for our HFSP grant - Princeton 2012!
4/30/12 - Congratulations to PhD student Chris Sosa for being awarded a very competitive DOE fellowship!
4/20/12 - Congrats to Brangwynne lab postdoc Steph Weber, whose PhD work in the Theriot lab on non-thermal fluctuations in bacteria has just been published in PNAS
4/18/12 - Cliff back after giving a talk at AbSciCon in Georgia - the only thing the audience will remember is "The Hoff" Slide!
3/26/12 - The Brangwynne lab leads an international team awarded a 3-year HFSP Program Grant to study RNA helicases in RNP bodies (see HFSP press release)
3/15/12 - Cliff becomes core faculty member of the Quantitative & Computational Biology (QCB) Program
3/12/12 - The Brangwynne lab welcomes Mol Bio rotation student Wen Yih Aw!
2/22/12 - Cliff officially becomes Associated Faculty member of the Molecular Biology Department
2/13/12 - Congratulations to Jeff Wang for being awarded a Stoll Fellowship!
1/25/12 - Congratulations to Marina Feric for passing her General Examination with flying colors!
1/17/12 - Cliff back from giving a seminar at McGill. Thanks to Gary Brouhard and colleagues for being fantastic hosts!
1/9/12 - The Brangwynne lab welcomes PhD student Chris Sosa!
11/21/11 - Cliff back from giving Physics of Living Cells seminar at UIUC. Thanks to Sua Myong and TJ Ha for hosting!
11/9/11 - Cliff back from giving a seminar at Johns Hopkins and hanging out with the Seydoux lab (thanks for the Oysters!)
11/2/11 - Cliff back after giving a seminar at UChicago. Thanks to Margaret Gardel and her fun and interesting colleagues for hosting!
10/29/11 - The Brangwynne lab welcomes undergradute Physics major William Gilpin!
10/28/11 - Farewell to visiting theorist Zi Chen who is off to do a postdoc with Larry Taber. Best of luck Zi!
10/26/11 - Cliff back from a productive and interesting Xenopus Resource Meeting at the MBL
10/21/11 - Thanks to honorary Branwynne lab member and DNA cloning Jedi Andrey Pozniakovskiy for spending the week with us (photo). Have fun during the rest of your visit to the US!
10/11/11 - Cliff back from an amazing Soft Matter Weitzfest weekend at Harvard (http://weitzfest.seas.harvard.edu/). Congrats to Dave Weitz for turning 60! (see infamous historical photo of "unknown authenticity")
10/10/11 - Confocal is installed and functional! (the best things come to those who wait)
10/1/11 - Welcome to undergraduate research assistant Jeff Wang!
9/20/11 - Welcome Senior Thesis Students Axel Shum and Jason Pan!
9/16/11 - The Brangwynne lab welcomes postdoctoral fellow Steph Weber!
6/29/11 - The Brangwynne lab welcomes high school student Ethan Li and undergraduate Ankita Gumaste
6/10/11 - Brangwynne lab went to the Mid Atlantic Soft Matter Meeting at Penn. Congrats to Daniel and Marina for their nice soundbite talks!
4/7/11 - Marina off to the CSHL Xenopus course, have fun!
4/6/11 - We received our Certificate of Occupancy and can move into the new lab! (see pics)
2/1/11 - Start of Professor Brangwynne's class CBE 433/533, Mechanics and Dynamics of Soft Living Matter
1/28/11 - Paper on nucleolus size and shape accepted at PNAS!
1/8/11 - PhD students Daniel Salas & Marina Feric join the lab!
1/1/11 - Official start of Brangwynne lab at Princeton