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Publications

2013


Phase transitions and size scaling of membrane-less organelles
Journal of Cell Biology 2013 (in press)
Brangwynne CP*


Spatial organization of the cell cytoplasm by position dependent phase separation
Physical Review Letters, 2013 (in press)
Lee C-F, Brangwynne CP, Gharakhani J, Hyman AA, Julicher F


A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells
Nature Cell Biology, 2013
[PDF] [C & EN Article] [The Atlantic] [The Scientist] [PrincetonU Homepage] [Dartmouth]
Feric M, Brangwynne CP* 


Nuclear Mechanics: Lamin webs and pathological blebs
Nucleus, 2013
Broedersz CP, Brangwynne CP*


The Micro and Macro of RNA Function
Molecular Biology of the Cell, 2013 [PDF]
Brangwynne CP*, Johnson TL*

2012


In Retrospect: The Origin of Life
Nature, 2012 [PDF] ["News" Coverage]
Hyman AA*, Brangwynne CP*


Attenuated short wavelength buckling and force propagation in a biopolymer-reinforced rod
Soft Matter, 2012 [PDF]
Shan WL, Chen Z, Broedersz CP, Gumaste AA, Soboyejo W, Brangwynne CP*


Getting RNA and Protein in Phase
Cell, 2012 [PDF]
Weber SC, Brangwynne CP*

2011


Beyond stereo-specificity: liquids and mesoscale organization of cytoplasm
Developmental Cell, 2011 [PDF]
Hyman AA*, Brangwynne CP*


Active Liquid-like Behavior of Nucleoli Determines their Size and Shape in Xenopus laevis Oocytes
Proceedings of the National Academy of Sciences USA, 2011 [PDF] [Current Biology Dispatch] [Nucleus Commentary] [F1000]
Brangwynne CP*, Mitchison TJ, Hyman AA


Soft active aggregates: mechanics, dynamics, and self-assembly of liquid-like intracellular protein bodies
Soft Matter, 2011 [PDF]
Brangwynne CP*

* = Corresponding author

Pre-2011

Centrosome size sets mitotic spindle length in Caenorhabditis elegans embryos
Current Biology, 2010 [PDF] [F1000]
Greenan G, Brangwynne CP, Jaensch S, Gharakhani J, Jülicher F, Hyman AA

Germline P granules are liquid droplets that localize by controlled dissolution/condensation
Science 2009 [PDF] [F1000]
Brangwynne CP, Eckmann CR, Courson DS, Rybarska A, Hoege C, Gharakhani J, Jülicher F, Hyman AA

Intracellular Transport by Active Diffusion
Trends in Cell Biology, 2009 [PDF]
Brangwynne CP, Koenderink GH, MacKintosh FC, Weitz DA

Mechanical response of cytoskeletal networks
Methods in Cell Biology, Vol. 89 Ch. 19, 2008 [PDF]
Gardel ML, Kasza KE, Brangwynne CP, Liu J, Weitz DA

Cytoplasmic diffusion: molecular motors mix it up
Journal of Cell Biology, 2008 [PDF]
Brangwynne CP, Koenderink GH, MacKintosh FC, Weitz DA

A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly
Journal of Cell Science, 2008 [PDF]
Groen AC, Needleman D, Brangwynne C, Gradinaru C, Fowler B, Mazitschek R, Mitchison TJ

Nonequilibrium microtubule fluctuations in a model cytoskeleton
Physical Review Letters, 2008 [PDF]
Brangwynne CP, Koenderink GH, MacKintosh FC, Weitz DA

Force fluctuations and polymerization dynamics of intracellular microtubules
Proceedings of the National Academy of Sciences USA, 2007 [PDF] [F1000]
Brangwynne CP, MacKintosh FC, Weitz DA

The cell as a material
Current Opinion in Cell Biology, 2007 [PDF]
Kasza KE, Rowat AC, Angelini TE, Liu J, Brangwynne CP, Koenderink GH, Weitz DA

Bending dynamics of fluctuating biopolymers probed by automated high-resolution filament tracking
Biophysical Journal, 2007 [PDF]
Brangwynne CP, Koenderink GH, Barry E, Dogic Z, MacKintosh FC, Weitz DA

A new microrheometric approach reveals individual and cooperative roles for TGF-beta1 and IL-1beta in fibroblast-mediated stiffening of collagen gels
FASEB Journal, 2007 [PDF]
Leung LY, Tian D, Brangwynne CP, Weitz DA, Tschumperlin DJ

Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement
Journal of Cell Biology, 2006 [PDF] [Current Biology Dispatch] [F1000]
Brangwynne CP, MacKintosh FC, Kumar S, Geisse NA, Talbot J, Mahadevan L, Parker KK, Ingber DE, Weitz DA

Glioma Expansion in Collagen I Matrices: Analyzing Collagen Concentration-Dependent Growth and Motility Patterns
Biophysical Journal, 2005 [PDF]
Kaufman LJ, Brangwynne CP, Kasza KE, Filippidi E, Gordon VD, Deisboeck TS, Weitz DA

Symmetry-Breaking in Mammalian Cell Cohort Migration During Tissue Pattern Formation: Role of Random-Walk Persistence
Cell Motility and the Cytoskeleton, 2005 [PDF]
Huang S§, Brangwynne CP§, Parker KK, Ingber DE

Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces
FASEB Journal, 2002 [PDF]
Parker KK, Brock AL, Brangwynne C, Mannix RJ, Wang N, Ostuni E, Geisse N, Whitesides GM, Ingber DE

Symmetry breaking in cultured mammalian cells
In Vitro Cell & Developmental Biology, 2000 [PDF]
Brangwynne C, Huang S, Parker KK, Ingber DE

Pictures in cell biology: squaring up to the cell shape debate
Trends in Cell Biology, 1999 [PDF]
Chen CS, Brangwynne C, Ingber DE

§ = Equal contribution