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Discovery of Lasso Peptide Isopeptidase

Grad student Mikhail Maksimov *15 and Professor Jamie Link  have isolated and characterized an enzyme, lasso peptide isopeptidase, that “unties” the lasso structure.  This enzyme suggests additional layers of regulation or perhaps new functions for lasso peptides. 

See more at http://pubs.acs.org/doi/abs/10.1021/ja4054256

For more infomation about Professor Link's research please see The Link Lab site.