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Mass Spectroscopy

The chemistry Mass Spectroscopy Facility consists of an array of spectrometers, managed by Dr. John Eng, and is focused on assisting the diverse research efforts of the chemistry department. New graduate students and postdoctoral researchers are encouraged to learn the operation of specific instruments and run their own samples during the course of their research. The resources of the facility also traditionally have been made available to researchers from other University departments. Professional help for running samples is always available and is usually the preferred method for the occasional user, or when individual training is required for specialized applications. Dr. Eng will run all samples for researchers from outside the department.

The following spectrometers are available in Frick Chemistry Laboratory, Room B14: 

 Agilent 6220 Accurate-Mass Time-of-Flight LCMS

Agilent 6220 Accurate-Mass Time-of-Flight LC/MS:
This is a user-operated, High Resolution Electrospray Ionization Mass Spectrometer, configured in a "walk-up" mode, that is available on a 24-hour basis. The training required for running your own samples on this instrument takes around 45 minutes to an hour. Individual lessons may be obtained by signing the training request sheet next to the instrument. Our synthetic chemists have been routinely obtaining sub ppm, accurate mass measurements when performing a complete characterization of their products for publication. The latest version of "Mass Hunter" software is available on this system and users are encouraged to use this instrument in the course of their research.


An Agilent 1100MSD Series Single Quadrupole LC/MS:
This instrument is configured for routine low resolution LC-MS applications in either the Positive or Negative ESI mode. Please contact the facility staff for scheduling and training on this popular instrument.


A Hewlett Packard 5989B- 5890 Gas Chromatograph-MS, currently optimize for high sensitivity GC-MS lipid Metabolomics and FAME analysis:
This is a reliable GC-MS which and be configured for most routine GC-MS full scan run and users require a brief training to be able to use this instrument.


An Agilent 7000 Triple Quadrupole GC/MS/MS with an Agilent 7890A GC equipped with 2-D column capability:
The central Mass Spectrometry Facility manages this advanced and very sensitive instrument, which is part of the Groves group instrument cluster. Researchers can access the GC/MS/MS by arrangements with the Groves group and scheduling with the facility.