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David MacMillan

Research Focus


Research in the MacMillan Group is centered on the field of organic synthesis and catalysis. We are inspired by the pursuit of new concepts in synthetic organic chemistry involving organocatalysis, organo-cascade catalysis, metal-mediated catalysis, and total synthesis of natural products and pharmaceuticals.

MacMillan Group Research Summary
  • The Advent and Development of Organocatalysis

    D. W. C. MacMillan
    Nature, 455, 304-308 (2008)
     
  • Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes

    D. Nicewicz, D. W. C. MacMillan
    Science, 322, 77-80 (2008)
     
  • Enantioselective Organocatalysis Using SOMO Activation

    T. D. Beeson, A. Mastracchio, J. Hong, K. Ashton, D. W. C. MacMillan

    Science, 316, 582-585 (2007)
     
  • Two Step Synthesis of Carbohydrates by Selective Aldol Reactions

    A. B. Northrup, D. W. C. MacMillan

    Science, 305, 1752-1755 (2004)
     
  • New Strategies for Organic Synthesis: The First Highly Enantioselective Organocatalytic Diels-Alder Reaction

    K. A. Ahrendt, C. J. Borths, D. W. C. MacMillan

    J. Am. Chem. Soc., 122, 4243-4244 (2000)
     

David MacMillan

MacMillan Lab Webpage
dmacmill@princeton.edu
Frick Laboratory 192
Phone: 609-258-2254

Faculty Assistant:
Caroline Phillips
cp@princeton.edu
Frick Laboratory, 191
Phone: 609-258-2254