The Biology, Detection and Treatment of Cancer
Speaker: Dr. Karen A. Malatesta, Princeton University
Series: Topical Seminars
Date/Time: Wednesday, March 13, 2013, 7:30 p.m. - 9:00 p.m.
Abstract: Cancer is the second most frequent cause of death worldwide: One in every two men and one in every three women will contract cancer during their lives. All types of human cancers but one arise from mutations occurring in normal cells in genes controlling cell proliferation. Although systemic chemotherapy is often used to treat cancer, it has several disadvantages, including severe side effects and low drug concentration delivered to the tumor. Localized treatment is more effective and preferable to limit these adverse effects. Several innovative nanomedical therapies, such as BioMEMS and nanoparticles, can provide effective cancer treatment.
Plappally, A., Chen, H., Ayinde, W., Alayande, S., Usoro, A., Friedman, K.C., Dare, E., Taiwo Ogunyale, T., Yakub, I., Leftwich, M., Malatesta, K., Rivera, R., Brown, L., Soboyejo, A., and Soboyejo, W. 2011. A field study on the use of clay ceramic water filters and influences on the general health in Nigeria. . J. Health Behav. & Pub. Health 1 (1) 1-14.
Paetzell, E., Botah, R., Odusanya, O.S., Anuku, N., Malatesta, K.A. and Soboyejo, W.O. 2012. Biosynthesis and adhesion of gold nanoparticles for breast cancer detection and treatment. J. Mater. Res. 27 (22): 2891-2901.
Yakub, I., Plappally, A., Leftwich, M., Malatesta, K., Friedman, K.C. Obwoya, S., Nyongesa, F., Usoro, A., Rivera, R., Piascowy, S., Maiga, A., Logothetis, S., Soboyejo, A.B.O., and Soboyejo, W. 2013. Porosity, flow and filtration characteristics of frustum-shaped ceramic water filters, J. Environ. Eng. In press.