More than 20 percent of Princeton Engineering faculty members, including engineers from all six departments, are engaged in research aimed at improving human health. Some engineers are advancing fundamental biology through the Lewis-Sigler Institute for Integrative Genomics, while others are using their expertise in nanotechnology to provide innovative solutions to long-standing problems in neuroscience, cancer treatment or vaccine delivery.
Electromagnetic pulses lasting one millionth of a millionth of a second may hold the key to advances in medical imaging, communications and drug development. But the pulses, called terahertz waves, have long required elaborate and expensive equipment to use. Researchers at Princeton University have drastically shrunk much of that equipment: moving from a tabletop setup with lasers and mirrors to a pair of microchips small enough to fit on a fingertip.
Two Princeton University studies are opening important new windows into understanding an untreatable group of common genetic disorders known as RASopathies that are characterized by distinct facial features, developmental delays, cognitive impairment and heart problems. The findings could help point the way toward personalized precision therapies for these conditions.
A tiny speck inside the cells of a tiny worm is shedding new light on the underlying mechanism that determines the size of various organisms. In a series of recent studies, scientists have unlocked the importance of the nucleolus, a tiny structure scattered throughout the nucleus, in cellular development. Now, researchers have found that the size of the nucleolus varies with the size of an organism, and within a given species, the nucleolus correlates with the size of an organism.