Combating Malaria: New ideas for an ancient problem
Speaker: Professor Manuel Llinas, Princeton University
Department: Electrical Engineering
Location: Engineering Quadrangle, J201
Date/Time: Wednesday, April 3, 2013, 7:30 p.m. - 9:00 p.m.
Malaria is one of the most devastating diseases of mankind, affecting nearly one in ten people worldwide and resulting in two to three million deaths annually. This disease is caused by the Plasmodium parasite of which Plasmodium falciparum is the deadliest form. While the past century has seen significant progress in anti-malarial drug development, many of these drugs are currently losing efficacy due to the rise of drug resistant P. falciparum strains. The challenge now is to identify and characterize novel targets for anti-malarial strategies. My lab is focusing on gene regulation and metabolism as potential avenues to disrupt the development of this deadly parasite. To accomplish this we are using a combination of whole-genome approaches and mass spectrometry-based metabolomics to explore the biology of this poorly characterized organism.