A tiny speck inside the cells of a tiny worm is shedding new light on the underlying mechanism that determines the size of various organisms. In a series of recent studies, scientists have unlocked the importance of the nucleolus, a tiny structure scattered throughout the nucleus, in cellular development. Now, researchers have found that the size of the nucleolus varies with the size of an organism, and within a given species, the nucleolus correlates with the size of an organism.
Trying to unravel the roles that a small set of genes play in the regulation of a human trait is a daunting enough task, but when scientists try to apply the same analytic methods to a specific tissue or organ, they quickly run into a storm of information. The functional role of any one gene is quickly obscured by a cascade of genes whose influence combines with that of other genes and environmental factors to affect multiple pathways. What starts as a few bits of information quickly becomes
Two members of the engineering faculty, Celeste Nelson and Clifford Brangwynne, have been named to the inaugural group of Faculty Scholars, a joint award from the Howard Hughes Medical Institute, the Simons Foundation and the Bill & Melinda Gates Foundation.
A study by biological engineers at Princeton solves a longtime paradox about how a key constituent of cells self-organizes intself into working structure despite being made of liquid. These insights into the form and function of the nucleolus could ultimately point toward new ways to treat disease.
When graduate student Yogesh Goyal told an audience at Princeton University in October how his research could help doctors diagnose patients with difficult-to-characterize congenital disorders, he was describing more than a potential medical breakthrough.
Princeton researchers have observed the artistry of developing lungs unfold in a petri dish and have arrived at a surprising conclusion about the forces that shape it.
Faculty members from several departments with expertise in biology and engineering will hold a day of lectures and discussions to celebrate bioengineering at Princeton on October 2, 2015.
A Princeton University-led research team has discovered an unexpected mechanism by which cells regulate an enzyme critical to early embryonic development in complex organisms, from yeast to humans. The work may inform new therapeutic strategies to fight cancer.
A team of biologists and engineers has developed a new method for measuring proteins that offers a long-sought tool for studying stem cells, cancer and other problems of fundamental importance to biology and medicine.
Princeton University physical scientists and engineers will partner with researchers at four other institutions to explore the driving forces behind the evolution of cancer under a five-year, $15.2 million award from the National Cancer Institute.
Celeste Nelson, an assistant professor of chemical engineering, has been chosen for the 2008 Fellowship in Science and Engineering by the David and Lucile Packard Foundation.
The American Institute of Chemical Engineers has selected Pablo Debenedetti to receive the 2008 William H. Walker Award for Excellence in Contributions to Chemical Engineering Literature.
Rochelle Murray's senior thesis project puts her on the font lines of a hot research area: the transmuting of waste material into clean-burning fuel.
Jianqing Fan, professor of operations research and financial engineering, received the Morningside Gold Medal of Applied Mathematics at the Fourth International Congress of Chinese Mathematicians. The medals are presented every three years to outstanding mathematicians of Chinese descent under age 45.
Mona Singh doesn't use the maps in her office to get from point A to point B -- she uses them to find meaning hidden in biological data, which may help advance the understanding of disease at the genetic level.
Incoming engineering professor Celeste Nelson has been selected by the Burroughs Wellcome Fund to receive a Career Award at the Scientific Interface. The grants foster the early career development of researchers with backgrounds in the physical and computational sciences who address biological questions in their work and are dedicated to careers in academic research.
Frontiers of health: Little lifesavers: Nanoparticles improve delivery of medicines and diagnotistcs
Tiny particles filled with medicine may also contain answers to some of the biggest human health problems, including cancer and tuberculosis. The secret is the size of the package. A team led by Robert Prud'homme, professor of chemical engineering and director of the Program in Engineering Biology, created the particles, which are only 100 to 300 nanometers wide -- more than 100 times thinner than a human hair.
The American Institute of Chemical Engineers has selected Christodoulos Floudas to receive its 2006 Computing in Chemical Engineering Award.
Clusters of students gathered in Princeton's Lewis Thomas Lab on a recent Friday for a trouble-shooting session before heading to their benches for another attempt at something few labs in the world can do: transforming mouse stem cells into muscle cells