Electromagnetic pulses lasting one millionth of a millionth of a second may hold the key to advances in medical imaging, communications and drug development. But the pulses, called terahertz waves, have long required elaborate and expensive equipment to use. Researchers at Princeton University have drastically shrunk much of that equipment: moving from a tabletop setup with lasers and mirrors to a pair of microchips small enough to fit on a fingertip.
Two Princeton University studies are opening important new windows into understanding an untreatable group of common genetic disorders known as RASopathies that are characterized by distinct facial features, developmental delays, cognitive impairment and heart problems. The findings could help point the way toward personalized precision therapies for these conditions.
A tiny speck inside the cells of a tiny worm is shedding new light on the underlying mechanism that determines the size of various organisms. In a series of recent studies, scientists have unlocked the importance of the nucleolus, a tiny structure scattered throughout the nucleus, in cellular development. Now, researchers have found that the size of the nucleolus varies with the size of an organism, and within a given species, the nucleolus correlates with the size of an organism.
Recent upgrades in imaging and fabrication facilities for atomic-scale research have made these labs among the best in the world and perhaps unique in their "one-stop-shop" combination of analysis and fabrication.
Trying to unravel the roles that a small set of genes play in the regulation of a human trait is a daunting enough task, but when scientists try to apply the same analytic methods to a specific tissue or organ, they quickly run into a storm of information.
The functional role of any one gene is quickly obscured by a cascade of genes whose influence combines with that of other genes and environmental factors to affect multiple pathways. What starts as a few bits of information quickly becomes
Two members of the engineering faculty, Celeste Nelson and Clifford Brangwynne, have been named to the inaugural group of Faculty Scholars, a joint award from the Howard Hughes Medical Institute, the Simons Foundation and the Bill & Melinda Gates Foundation.
Princeton engineers have found that, in breast cancer, tumor hardness and lack of oxygen trigger a biological switch that causes certain cells to embark on a cancer-promoting program.
Investigators eager to uncover the genetic basis of autism could now have hundreds of promising new leads thanks to a study by Princeton University and Simons Foundation researchers.
Researchers from Princeton University are joining with colleagues from U.S. government laboratories in an effort to dramatically improve the test for the Ebola virus. The goal is to offer a quick, accurate and inexpensive method to help contain future epidemics.
A study by biological engineers at Princeton solves a longtime paradox about how a key constituent of cells self-organizes intself into working structure despite being made of liquid. These insights into the form and function of the nucleolus could ultimately point toward new ways to treat disease.
Researchers at the intersection of engineering and biology are setting the groundwork for advances in health and medicine, including curing diseases such as Alzheimer's, growing replacement organs and preventing developmental abnormalities.
When graduate student Yogesh Goyal told an audience at Princeton University in October how his research could help doctors diagnose patients with difficult-to-characterize congenital disorders, he was describing more than a potential medical breakthrough.
Princeton researchers have observed the artistry of developing lungs unfold in a petri dish and have arrived at a surprising conclusion about the forces that shape it.
Faculty members from several departments with expertise in biology and engineering will hold a day of lectures and discussions to celebrate bioengineering at Princeton on October 2, 2015.
Research presented at the Innovation Forum ranged from sustainable furniture production to groundwater bioremediation. A member of each team delivered a three-minute pitch to a panel of judges consisting of investors and business leaders, who then awarded prize money to their top choices.