The Kruglyak Lab conducts experients in model organisms, as well as computational analyses, aimed at understanding how changes at the level of DNA are shaped by molecular and evolutionary forces, and how these changes lead to all the observable differences among individuals within a species.
News
Kruglyak work on NHGRI panel featured in Nature
Leonid Kruglyak was part of an expert panel the National Human Genome Research Institute (NHGRI) convened earlier this year on the problem of missing heritability. The missing heritability problem refers to the fact that despite major technology advances made possible by the Human Genome Project, and studies of tens of thousands of individuals, the great majority of the genetic factors responsible for differences between individuals in disease susceptibility and in normal traits such as height have not been found.
Their work has led to a review article in Nature , “Finding the Missing Heritability of Complex Diseases,” reporting the panel's conclusions about the likely sources of this problem and the most promising future research directions for the human genetics community to uncover the genetic basis of human variation. (10/07/09)
Postdocs Erik Andersen and Ian Ehrenreich received Ruth L. Kirschstein National Research Service Awards from the NIH. (09/09)
Graduate student Zia Khan's research is featured in the Journal of Proteome Research. (09/09)
