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April 6th 2015: Anjali receives NSF!

Former undergraduate in the lab, Anjali Bisaria, receives an NSF Fellowship.  Anjali is now a graduate student at Stanford University.  Congratulations Anjali!

November 21, 2013: Celebrate Princeton Invention

Megan and Michael presented the optogenetic control technology at Celebrate Princeton Invention. Pictures and a brochure featuring our technology can be found on the event's website .

November 20, 2013: University of Pennsylvania

Megan presented in the Condensed Matter Seminar series in the Department of Physics and Astronomy at the University of Pennsylvania.

November 13, 2013: Back to Harvard!

Megan returned to Harvard to present a seminar for the "Home and Away" series between Princeton and Harvard.

November 6, 2013: University of Virginia

Megan presented a seminar in the Chemistry Department at the University of Virginia.

October 18, 2013: Princeton Area Yeast Meeting

Megan shared the optogenetic control technology at the Princeton Area Yeast Meeting.


October 16, 2013: Burroughs Wellcome Fund New Awardee Meeting

Megan attended the BWF New Awardee meeting in Research Triangle Park, NC.  It was a great opportunity to meet new awardees and share exciting science!

October 4, 2013: Megan presents at the PA Biophysical Society Regional meeting

Megan gave one of only three selected talks at the Pennsylvania Biophysical Society regional networking meeting at Penn State, University Park.  She talked about the optogenetic protein concentration control technology.  The talk was well-received by the audience!

August 10, 2013: Megan presents at the 7th Annual Q-Bio Conference

Megan gave a selected talk entitled "Real-time optogenetic control of intracellular protein concentration in microbial cell cultures" at the Q-Bio conference in Santa Fe, NM.  Abstracts and the meeting agenda are available here: QBio 2013

August 9, 2013: Microfluidics bootcamp successfully completed!

Bootcamp Session #1

The annual microfluidics bootcamp was a success. Michael completed the course as a student, while Megan served as an instructor.

July 12, 2013: The QCB301 students' comparative genomics paper is out!

The QCB301 students' hard work characterizing gene expression in S. bayanus in response to a diverse range of stimuli is available online at Genetics! Congratulations students!

July 11, 2013: Megan presents at the National Centers for Systems Biology Meeting

Megan presented a lightning talk at the National Centers for Systems Biology Annual Meeting in Bethesda, MD July 11-12. You can watch a video of the conference, including the lightning talks, here

June 14, 2013: JOVE Article is online!

Scott, Ping, and Megan's JOVE article on in situ hybridization for visualization of single mRNA molecules is now online! JOVE Video

June 3, 2013: QCB and Molecular Biology Class Day

graduation 2013
Bohao, Joseph, Megan, Patrick

Patrick, Bohao, and Joseph graduate!  All three completed senior thesis projects in the McClean lab and received the QCB certificate.  Bohao's thesis won the Molecular Biology Award for Excellence in Senior Thesis Research and the QCB Best Senior Thesis awards!  Joseph is off to Harvard for graduate school, Patrick is off to McKinsey & Company, and Bohao will stay on in the McClean lab for a year before heading off to an MD/PhD program.  Congratulations!

May 23, 2013: Megan received a Career Award at the Scientific Interface (CASI) from the Burroughs Wellcome Fund

BWF smaller

Megan was one of ten recipients of a Career Award at the Scientific Interface from the Burroughs Wellcome Fund.  Awards are given to early career researchers working at the interface of the physical and biological sciences and provide $500,000 of research funding over 5 years.  The announcement is available here!

April 24, 2013: Natalia's paper is out!

Natalia's paper "Noise and interlocking signaling pathways promote distinct transcription factor dynamics in response to different stresses" is available online at Molecular Biology of the Cell!   Congratulations Natalia!

March 14, 2013: Agnes' paper is out!

Agnes' paper "Severe osmotic compression triggers a slowdown of intracellular signaling, which can be explained by molecular crowding" is available online at PNAS ! Congratulations Agnes!

February 6, 2013: Biophysical Society Meeting

Megan presented "Real-time light-driven temporal control of gene expression and protein concentration in S. cerevisiae" at the Biophysical Society meeting in Philadelphia, PA.


February 6, 2013: NJEN Poster and Pitch Contest

Michael presented a poster entitled "Optogenetic Protein Induction System and a Robotic Bioreactor Device Used to Control Protein Levels within a Population of Cells" at the NJEN (New Jersey Entrepreneurial Network) Poster Session and Pitch Contest at Princeton University.

January 22, 2013: Jove Filming!

Megan and Scott McIsaac were in front of the camera to film "Visualization and analysis of mRNA molecules using fluorescence in situ hybridization in Saccharomyces cerevisiae" for the Journal of Visualized Experiments (JOVE).  Look for the article online soon!

December 16, 2012: American Society for Cell Biology Meeting

Megan presented "Real-time light driven temporal control of gene expression and protein concentration in S. cerevisiae" at the American Society for Cell Biology Meeting in San Francisco, California.

December 6, 2012: NJTC Regional Commercialization Conference

Michael presented "An Optogenetic Solution for Real-Time Population-Level Gene Expression Control" at the NJTC (New Jersey Technology Council) Regional Commercialization Conference in Wilmington, Delaware.

October 22, 2012: Biotech2012 Innovation Corridor

The McClean lab's optogenetic technology won a "Technology Recognition" award in the Innovation Corridor at Biotech2012 in Philadelphia.  The title of the presentation was "Optogenetic protein induction system and a robotic bioreactor device used to control protein levels within a population of cells" .

October 16, 2012: SmartStat Technology

The docket (Princeton Docket #13-2838 ) for the SmartStat technology is available from the Princeton Office of Technology Licensing.

August 5, 2012: Stressed Out!

Megan gave a platform presentation entitled "Transcription factor localization dynamics govern the transcriptional response to environmental changes" in the "Stressed Out" session at the Yeast Genetics and Molecular Biology Meeting.

August 2, 2012: Design, Build, Test!

Justin Melendez gave a talk entitled "Real-time light-driven temporal control of gene expression and protein concentration in S. cerevisiae" in the "Synthetic Biology: Design, Build, Test" workshop at the Yeast Genetics and Molecular Biology Meeting.

July 27, 2012: Provisional Patent Filed

The McClean lab's (J. Melendez, B. Oakes, and M. McClean) provisional patent (#61/676, 566) was filed  with the United States Patent and Trademark Office.

June 5, 2012: Anjali Graduates!

Anjali Graduation
Anjali's thesis was well received!

Anjali's senior thesis won the QCB Thesis Prize and the Molecular Biology Department's award for excellence!  Congratulations Anjali!  She is off to bigger and better things and we will miss her!

December 5, 2011: UC Irvine Talk

Megan gave an invited talk entitled "Probing pathway components to understand information processing in signaling pathways" at the Center for Complex Biological Systems at the University of California, Irvine.

October 30, 2011: CIFAR Meeting

Megan gave an invited talk at the CIFAR Genetic Networks Program Meeting at the Center for Genomics and Systems Biology (New York University, New York, New York) entitled “Probing Pathway Components to Understand Information Processing in Signaling Pathways".