11/25/13 The Lewis-Sigler Institute was endowed through a generous gift from Peter B. Lewis, class of 1955, to honor his dear friend and Princeton roommate, Paul B. Sigler, class of 1955. The founding gift to the Institute is just one of several major contributions that he made to Princeton University and beyond. (Full story)
11/14/13 - The What Would I Say? app was created by Princeton graduate students Harvey Cheng (EE), Ugne Klibaite (QCB), Alex Furge (ORFE), Daniel Jiang (ORFE), Pawel Przytycki (COS), Vicky Yao COS) and Edward Young (PHY) during this year’s HackPrinceton event. The app takes a users’ old Facebook status updates and produces new phrases out of them.
11/1/13 - William Bialek, the John Archibald Wheeler/Battelle Professor in Physics and the Lewis-Sigler Institute for Integrative Genomics, is the recipient of the 2014 Swartz Prize for Theoretical and Computational Neuroscience from the Society for Neuroscience.
10/24/13 - Olga Troyanskaya, Professor of Computer Science and the Lewis-Sigler Institute for Integrative Genomics, is the recipient of the 2014 Ira Herskowitz Award from the Genetics Society of America, for her outstanding contribution in the field of yeast research.
10/4/13 - Nano-dissection identifies genes involved in kidney disease (Genome Research)
Understanding how genes act in specific tissues is critical to our ability to combat many human diseases, from heart disease to kidney failure to cancer. Yet isolating individual cell types for study is impossible for most human tissues.
09/05/13 - A group of researchers who recently joined the Institute has uncovered unusual activity in the functioning of nuclear pores, the sophisticated tunnels that shuttle proteins, RNA (ribonucleic acid), and other molecules between the cytoplasm and nucleus inside of cells. The research adds to our understanding of how DNA is organized inside cells.
08/15/13 - A group of Lewis-Sigler Institute researchers have joined with university undergraduates to publish "A New System for Comparative Functional Genomics of Saccharomyces Yeasts" in the journal Genetics. With genome sequencing in humans and other organisms quickly becoming easier and cheaper, the next big challenge for biology is to translate genome sequences into gene functions. The researchers tackled this problem in a novel way by harnessing the power of undergraduate researchers.
7/22/13 - In a twist on "survival of the fittest," Princeton University researchers have discovered that evolution is driven not by a single beneficial mutation but rather by a group of mutations, including ones called "genetic hitchhikers" that are simply along for the ride. The study was published July 21 in the journal Nature.
06/19/13 - David Botstein, Princeton University's Anthony B. Evnin '62 Professor of Genomics and the current director of the Lewis-Sigler Institute for Integrative Genomics, is a recipient of the 2013 Warren Alpert Foundation Prize in recognition for his work that helped establish a framework for the Human Genome Project. Botstein shares the prize with Stanford Univesity School of Medicine faculty members Ronald Davis and David Hogness.
4/18/13 - Princeton University neuroscientists are poised to play a leading role in revolutionizing our understanding of the human brain as outlined in President Barack Obama's BRAIN Initiative.