4/28/15 - A multi-year effort by researchers from Princeton and other universities and medical schools has taken a big step toward extracting knowledge from these big data collections and opening the door to new understanding of human illnesses. Led by Olga Troyanskaya in the Lewis-Sigler Institute of Integrative Genomics, the team used integrative computational analysis to identify how genetic circuits function and change in different tissues relevant to disease. Published in Nature Genetics.
April 2, 2015 - A study published in Nature Genetics by Minsun Song, Wei Hao and John Storey reports a powerful new approach for performing Genome-wide association studies (GWAS) while automatically accounting for hidden population structure. They illustrate the power of their method, the genotype-conditional association test, or GCAT, on simulated data and then apply it to large genotype datasets for both quantitative and binary traits.
March 30, 2015 - Mechanics Matter: The action potential is associated with action waves. Benjamin Machta a Theory Fellow from the Lewis-Sigler Institute and Ahmed El Hady from the Princeton Neuroscience Institute have proposed a theoretical model to understand the physical origins of mechanical displacements associated with action potential propagation.
February 13, 2015 - Michael Levine will become the next Director of the Lewis-Sigler Institute for Integrative Genomics in July, 2015. Levine, who will also have an appointment in the Molecular Biology Department, will join Princeton from the University of California at Berkeley.
December 22, 2014 – Science Careers has named Shirley Tilghman, President Emerita and Professor of Molecular Biology and Public Affairs, as their Person of the Year. This annual award is to “honor an individual who has made an especially significant and sustained contribution to the welfare of early-career scientists.”
December 12, 2014 - A new computer-based technology for recording and evaluating animal movements could help researchers conduct studies of the genes and neural circuits that drive behaviors. (Research from Joshua Shaevitz and colleagues in the Lewis-Sigler Institute for Integrative Genomics.)
John Storey chosen for endowed professorship, the William R. Harman '63 and Mary-Love Harman Professor in Genomics
October 8, 2014 - John Storey, Professor in the Lewis-Sigler Institute for Integrative Genomics and Director of the Center for Statistics and Machine Learning, has been named to the endowed professorship, the William R. Harman '63 and Mary-Love Harman Professor in Genomics.
August 21, 2014 - Princeton faculty members William Bialek and Mala Murthy have been awarded Early Concept Grants for Exploratory Research (EAGER) by the National Science Foundation (NSF) to enable new technologies to better understand how complex behaviors emerge from the activity of brain circuits.
Professor John Storey of the Lewis-Sigler Institute and Department of Molecular Biology to head new Center for Statistics and Machine Learning
July 22, 2014 - Princeton University has established the Center for Statistics and Machine Learning. John Storey, a professor of molecular biology and the Lewis-Sigler Institute for Integrative Genomics, has been named the center's director.
Ned Wingreen, Acting Director of Lewis-Sigler Institute, part of team awarded Schmidt Funds to Support New Research Technologies
May 2, 2014 - Ned Wingreen, Acting Director of LSI, Bonnie Bassler, Professor of Molecular Biology, and Howard Stone, Professor of Mechancial and Aerospace Engineering were awarded Schmidt Transformative Technology Funds to develop a microscope for probing bacterial biofilms.