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Biography

Joshua D. Rabinowitz

EDUCATION

Stanford University
M.D., 2001
Ph.D. in Biophysics, 1999

University of North Carolina at Chapel Hill
B.A. with Highest Honors in Mathematics, 1994
B.A. in Chemistry, 1994

RESEARCH POSITIONS

Princeton University
Department of Chemistry & Lewis-Sigler Institute for Integrative Genomics
     Professor, 2011–present
     Associate Professor,  2009–2011
     Assistant Professor, 2004–2009
Department of Molecular Biology
     Associated Faculty, 2005–present
     Comprehensive studies of cellular metabolism

Alexza Pharmaceuticals
Co-founder and Vice President, Research, 2000–2004
- Accelerating onset of drug action through thermally generated aerosols

HONORS, AWARDS, AND FELLOWSHIPS

Agilent Thought Leader Award, 2013

Kavli Frontiers of Science Scholar, Kavli Foundation and National Academy of Sciences, 2008

CAREER Award, National Science Foundation, 2007–2013

Beckman Young Investigator Award, Arnold and Mabel Beckman Foundation, 2005–2009

Medical Scientist Training Program (MSTP) Trainee, National Institutes of Health, 1994–2001

Churchill Fellow (Declined), 1994

Barry M. Goldwater Scholar, Federal Excellence in Education Foundation, U.S. Federal Government, 1993–1994

President, Phi Beta Kappa, University of North Carolina, 1993–1994

Herbert Worth Jackson Scholar, University of North Carolina Honors Program, 1990–1994

PUBLICATIONS

See publications tab.

RECENT INVITED TALKS
American Association for Cancer Research (2014)
Yale University, Department of Chemistry (2013)
University of Pennsylvania, Dept. of Biochemistry & Biophysics (2013)
Cancer Research UK, Cambridge University (2013)
University of Pennsylvania, ITMAT Symposium (2013)
Harvard Medical School, Dept. of Systems Biology (2013)
Duke University School of Medicine, Depts. of Pharmacology & Cancer Biology (2013)
Cancer Institute of New Jersey (2013)
Systems Biology of Infection Symposium, Switzerland (2013)
MIT, Koch Institute for Integrative Cancer Research (2013)
American Society for Microbiology (2013)
American Society for Biochemistry and Molecular Biology Conference (2013)
Keystone Symposium on Tumor Metabolism (2013)
University of Chicago (2012)
United Mitochondrial Disease Foundation (2012)
Memorial Sloan-Kettering Cancer Center (2012)
American Association for Cancer Research, Annual Meeting (2012)
New York Academy of Science (2012)
AFOSR Bioenergy Program Review (2011)
CONO 2011 / Viral Ed Conference (2011)
Rockefeller University (2011)
SU2C Team Meeting (2011)
PhytoMetaSyn Project, Annual Meeting (2011)
Broad Institute (2011)
NJ Governor’s Conference on Effective Partnering in Cancer Research (2011)
Case Western University (2011)
International Conference on Systems Biology, Edinburgh (2010)
Metabolomics Society, Amsterdam (2010)
IEEE International Conference on Bioinformatics & Bioengineering (2010)
American Association for Cancer Research, Washington, DC (Speaker & Session Chair) (2010)
New York Academia of Sciences, Hot Topic Symposium, Learning from the Metabolome (2010)
Department of Energy, Genomic Sciences Meeting (Plenary Speaker) (2010)
Cold Spring Harbor Laboratory (2009)
National Institutes of Health, Cancer Cell Metabolism Workshop (2009)
Dana Farber Cancer Institute, Kidney Cancer Program 
   (Keynote Speaker) (2009)
University of Pennsylvania, Institute for Diabetes,
   Obesity & Metabolism (2009)
University of Tennessee, Department of Chemistry (2009)
Vanderbilt University, Institute of Chemical Biology (2009)
Stanford University, Department of Bioengineering (2008)
University of California-Berkeley, Department of Microbiology (2008)
Harvard University, Medical School, Department of Cell Biology (2008)
University of California-San Diego, Department of Bioengineering (2008)
Institute for Advanced Study, Department of Systems Biology (2008)
University of Pennsylvania, Medical School, Cancer and Diabetes Metabolism
   Seminar (2008)
Scripps Research Institute, Center for Mass Spectrometry (2008)
Harvard University, FAS Center for Systems Biology (2008)

INVENTORSHIP

Inventor of 134 patents issued by U.S. Patent and Trademark Office

Inventor of five drug products in FDA-sanctioned clinical testing.
- The most advanced product treats acute agitation in bipolar and
   schizophrenic patients.  It has successfully completed two phase 3
   clinical trials and will be submitted for FDA approval shortly.
- The other products (several of which are in Phase II trials) treat migraine
   headache, panic attacks, insomnia, and cancer pain.

ACTIVE GRANTS

Co-Investigator, NIH, 05/2012–03/2017
University of Pennsylvania Diabetes Research Center

Principal Investigator, NIH, 08/2012–04/2017
Identification of Metabolic Vulnerabilities of Ras-Driven Cancer Cells

Principal Investigator, NIH, 08/2012–07/2016
Mechanisms and Consequences of Metabolic Manipulation by Human Cytomegalovirus

Co-Investigator, DOE, 4/2011–11/2014
Metabolomics of Clostridial Biofuel Production

Principal Investigator, University of Pennsylvania
Stand Up to Cancer, 12/2009–11/2014
Identifying and Treating Glutamine-dependent Pancreatic Cancer

Co-Investigator, NSF CDI-Type II, 9/2009–8/2014
MS-Omics Hub for Cyber-enabled Acceleration of Mass Spectrometry-Based Metabolomics and Proteomics

Participant, National Institutes of Health Center Grant, 9/2004–8/2014
Center for Quantitative Biology

Co-Investigator, NIH, 8/2012–7/2014
Radiation Response within the Tumor microenvironment

Co-Investigator, NIH, 6/2012–6/2014
Thyroid hormone receptors—regulation and function

Co-Investigator, NIH, 7/2013–6/2014
Molecular mechanism of TRAF3 in the regulation of mitochondria function in B lymphocytes

TEACHING

Undergraduate: A Quantitative, Integrative Introduction to the Sciences,
Parts V and VI (with D. Botstein and E. Weischaus)
A uniquely mathematics-intensive introduction to genetics, physiology, and organic and biological chemistry for college sophomores

Graduate: Biophysical Chemistry I and II
A quantitatively rigorous treatment of biological chemistry for first year science graduate students