Tim Stearns, Stanford, Centrosomes, Cilia and Cell Signaling
The central question behind our work is how the centrosome and primary cilium control cell function and influence development, and how defects in these structures cause a remarkable range of human disease phenotypes, ranging from cancer, polycystic kidney disease, and obesity, to neurocognitive defects including mental retardation, schizophrenia, and dyslexia. The talk will cover fundamental questions including 1) how is an organelle duplicated exactly once per cell cycle? 2) how are signaling pathway components concentrated sub-cellularly to effect efficient signaling and 3) how can we use genomic analysis of specialized cell types to understand cell structure and function?
Location: Carl Icahn Lab 101
Date/Time: 11/12/12 at 4:15 pm - 11/12/12 at 5:15 pm
Category: Quantitative & Computational Biology
Department: Lewis-Sigler Institute