IIP Internships in Singapore
A*STAR Institute of Medical Biology (IMB)
Location: Singapore, Singapore
About: IMB is an institute in the biomedical sciences cluster of Singapore’s Agency for Science, Technology, and Research (A*STAR). It started operating in 2007 with a coalescence of research programs from the Centre for Molecular Medicine and the laboratories of the Singapore Stem Cell Consortium. It has been joined by groups from top institutions in Singapore and the U.S. and from the biotechnology industry.
Intern Responsibilities: The overarching goal of the lab in which IIP interns would be placed is to develop efficient protocols that convert pluripotential hESCs into functional beta cells. If produced in bulk and in a clinically-compliant fashion, these cells could provide an inexhaustible supply of material for the treatment of type 1 diabetes. The lab focuses on three general questions: (1) how to produce bona fide DE from hESC; (2) how to assign pancreatic fate to this progenitor population; and (3) how to specifically direct the progressive specification of early pancreatic cells toward the mature beta cell fate. IIP interns will be paired with a senior member of the lab to pursue one of these fast-moving projects.
Qualifications: Applicants should have competency in basic molecular biology and a keen interest in biomedical research.
Additional background information on the project: A renewable supply of pancreatic beta cells would be invaluable for treating type 1 diabetes. However, despite considerable effort, it is not yet possible to generate functional beta cells from human Embryonic Stem Cells (hESC) in vitro. Interestingly, experiments conducted in mice demonstrate that interactions with the surrounding mesenchyme and endothelium orchestrate pancreatic development. The proposed project seeks to identify signals secreted by these tissues and determine how they affect beta cell development. Specifically, microtissues will be generated from different cell types and used to study the interactions between them. The first component of the project involves culturing and differentiating different cell types for inclusion in 3D microtissues. Microtissues will then be treated with inhibitors of signal transduction to determine the dynamics of cell-cell signaling during lineage commitment. The identity and behavior of different cell types will be determined by a combination of genein the words of a past intern): Intern #1- I'm responsible for the wet lab work, which has mostly been cell culture (feeding & passaging cells) and imaging (eosin staining, immunohistochemistry). My supervisor has now put me in charge of his various experiments: he instructs me on what to do at the beginning of the day and I spend the rest of the day doing it. This includes culturing and differentiating mesenchymal stem cells, endothelial cells and human embryonic stem cells, combining them into organoid bodies, sorting cells via fluorescence activated cell sorting (FACS), fixing cell aggregates in wax, sectioning and staining, and visualization via phase contrast and fluoresence microscopy.
Previous work experiences (in the words of a past IIP intern): I tried to differentiate pancreatic beta cells from human embryonic stem cells, using a protocol provided by someone who collaborates with the lab I was in. Every day, I also did tissue culturing to maintain a few stem cell lines. In addition, I have learned techniques that aren't related to my project but that are still very common and useful, including in situ hybridization of mouse and zebrafish embryo, and immunofluorescence...My postdoc was trying to compare the efficacies of two different differentiation protocols for taking stem cells to pancreatic beta cells. I carried out one of the differentiation protocols, while someone else in the lab is doing the other...Tangibly, I learned a number techniques, including tissue culturing, RT-qPCR, flow cytometry, in situ hybridization, and immunofluorescence, working with stem cells, and mouse and zebrafish embryo. More generally, I learned how long it takes to make progress in science and how often things can go wrong.
|For UPDATED information on SUMMER 2016 and TO APPLY, click here: A*Star IMB|
Location: Singapore, Singapore
aidha is a not-for-profit organization that delivers financial and entrepreneurship education to women migrant workers who want to expand their economic opportunities and build brighter futures for themselves and their families. Inspired by UNIFEM’s National Committee, aidha provides confidence-building, money management, entrepreneurship training, and the micro-credit services necessary to launch small businesses. aidha is looking for IIP candidates who have interests in any of the following areas: business, law, research, marketing, women empowerment, education, and migration issues. Singapore is an English-speaking country, but an intern with Mandarin, Tamil, Bahasa, or Bangla language skills would be equipped to make a unique contribution. Three placements have been established for International Internship Program (IIP) interns, who will work on either core team projects, operations and teaching, or an independent project in any of the following five areas:
- Program Development
- Human Resources
|For UPDATED information on SUMMER 2016 and TO APPLY, click here: Aidha - Singapore|
Impact Investment Exchange (IIX) Asia | Impact Investment Shujog (Shujog)
Location: Singapore, Singapore
IIX is a Singapore-based Social Enterprise (SE) dedicated to creating vibrant social capital markets in Asia Pacific. The company’s three investment capital-raising platforms allow SEs to raise capital by amplifying their social and environmental impact and giving them greater opportunities to scale and expand their work. IIX’s internship program focuses on developing and stimulating products and platforms that will create a more transparent and engaged marketplace for impact investments to take place. One IIP placement has been made available in one of the following departments.
- Investor Relations Team: Assist the Impact Partners team to conduct investor outreach and education. This will include direct engagement with investors, high-net worth individuals, and banks, so fluency in finance is needed. This individual will also work with and assess social enterprises to prepare them for Impact Partners listing (examining financial reports, business plans, understanding capital needs). Marketing deals listed on the platform will also be a key role.
- Social Enterprise/Issuer Team: Work with the Social Enterprise team on evaluating social enterprises, guiding them to become investor-ready and managing their capital raising processes. This work will include financial valuation, social impact assessment, process management, and building trusting relationships.
- Business Development Team: The IIX Business Development team initiates and cultivates important relationships and initiatives that will result in strategic partnerships. The business development team supports the development of new products, services, and projects that IIX is researching and/or test-launching. Outreach to build a local and regional network of ecosystem partners who will contribute and support the long-term sustainability of SEs will also be a critical role. Demonstrated project management skills are required in this role.
- Assessment and Research Team: Conduct research and analysis of the social enterprise sector in Asia. This includes country-wide, sector-specific or ecosystem-targeted research as well as broader policy perspectives. These research efforts culminate in published reports that are widely disseminated across the region. In addition, work closely on refining and implementing the Shujog Assessment, which helps social enterprises measure and communicate their social and environmental impact.
- Marketing and Communications Team: Work with the Shujog team to continue building strategic messaging and initiatives that promote the impact investing and social enterprise space in Asia. Work closely across all functions of both IIX and Shujog to continue building a cohesive and compelling story of how social capital markets will influence sustainable development in Asia.
- Business Development Team: Work with the Shujog Business Development team to initiate and cultivate important relationships and initiatives that will result in strategic partnerships with Shujog. Aid in promoting and developing Shujog products and services that fulfill a need in the social enterprise and impact investment community in Asia.
View a PowerPoint (.pdf) by a past IIP intern:
|For UPDATED information on SUMMER 2016 and TO APPLY, click here: Impact Investment|