Interstate 72

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Interstate 72 marker

Main route of the Interstate Highway System
Main • Auxiliary • Business

Interstate 72 (I-72) is an Interstate Highway in the midwestern United States. Its western terminus is in Hannibal, Missouri, at an intersection with U.S. Route 61; its eastern terminus is at Country Fair Drive in Champaign, Illinois.


Route description


I-72 runs for just over 2 miles (3 km) in the state of Missouri. Its western terminus is an interchange with U.S. Route 61 to the Mark Twain Memorial Bridge over the Mississippi River. This bridge connects the city of Hannibal with Illinois.


In the state of Illinois, I-72 runs for 182 miles (295 km). The portion of I-72 and I-172 from Springfield to Quincy, Illinois is commonly referred to as the Central Illinois Expressway (CIE). As of 2007, I-72 has one business route — Business Loop 72 in Jacksonville.


Based on the 157-mile (253 km) marker at Missouri 79, when US 36 is upgraded to Interstate standards across Missouri, the future western terminus of I-72 would be at Cameron, Missouri at the intersection with I-35.

The concept of I-72 across Missouri was to create the Chicago-Kansas City Expressway, a rural 4-lane highway across northern Missouri and west central Illinois from Cameron, Missouri at I-35 to Springfield, Illinois at I-55. This would provide a series of rural 4-lane highways (I-35, US 36, I-72, and I-55) connecting Chicago to the North American Free Trade Agreement (NAFTA) Corridor (High Priority Corridor 23). This would reduce the amount of through traffic, primarily truck traffic, in the St. Louis, Des Moines, and Quad Cities metropolitan areas by serving as an alternate route for I-70 and I-80.

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