Issaquena County, Mississippi

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Issaquena County is a county located in the Mississippi Delta region of the U.S. state of Mississippi. As of 2000, the population was 2,274. In population, it is the smallest county in Mississippi. Its county seat is Mayersville[1]. Issaquena is a Native American word which means Deer River.



According to the U.S. Census Bureau, the county has a total area of 441 square miles (1,142.2 km2), of which 413 square miles (1,069.7 km2) is land and 28 square miles (72.5 km2) (6.41%) is water.

Major highways

Adjacent counties


As of the census[2] of 2000, there were 2,274 people, 726 households, and 509 families residing in the county. The population density was 6 people per square mile (2/km²). There were 877 housing units at an average density of 2 per square mile (1/km²). The racial makeup of the county was 36.32% White, 62.75% Black or African American, 0.09% Native American, 0.22% from other races, and 0.62% from two or more races. 0.44% of the population were Hispanic or Latino of any race.

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