Rosalind Franklin

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Rosalind Elsie Franklin (25 July 1920 – 16 April 1958) was a British biophysicist, physicist, chemist, biologist and X-ray crystallographer who made critical contributions to the understanding of the fine molecular structures of DNA, RNA, viruses, coal and graphite.

Franklin is still best known for her work on the X-ray diffraction images of DNA. Her data, according to Francis Crick, were "the data we actually used"[1] to formulate Crick and Watson's 1953 hypothesis regarding the structure of DNA.[2] Furthermore, unpublished drafts of her papers (written as she was arranging to leave the unsupportive research situation at King's College London) show that she had indeed determined the overall B-form of the DNA helix. However, her work was published third, in the series of three DNA Nature articles, led by the paper of Watson and Crick which only vaguely acknowledged her evidence in support of their hypothesis.[3] The possibility that Franklin played a major role was not revealed until Watson wrote his personal account, The Double Helix,[4] in 1968 which subsequently inspired several people to investigate DNA history and Franklin's contribution. The first, Robert Olby's "The Path to the Double Helix", supplied information about original source materials for those that followed.[5] After finishing her portion of the DNA work, Franklin led pioneering work on the tobacco mosaic and polio viruses.

She died at the age of 37 from complications arising from ovarian cancer.


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