Polychlorinated biphenyls (PCBs) are mixtures of synthetically chlorinated chemical compounds. They usually take the form of oily liquids or waxy solids and have been used as coolants and lubricants in electrical equipment because of they are effective insulators and tend not to burn easily. The U.S. stopped all manufacturing of PCBs in 1997 because of increasing concerns about their toxicity. More than 1.5 billion pounds of PCBs were manufactured in the US alone, prior to its banning in 1977.[1]


The most widely noticed health effect of PCB exposure is aggravated skin, including acne and rashes. Experiments in animals show that large amounts of consumed PCBs can result in anemia, as well as liver, stomach, and thyroid gland damage. It is also suspected that extensive PCB exposure is correlated with changes in the immune system, behavior, and reproduction complications.[4]
Sources:
[1] http://www.nsc.org/library/chemical/polychlo.htm
[2] http://www.inchem.org/documents/ehc/ehc/ehc140.htm#1.1.2
[3] http://www.epa.gov/opptintr/pcb/pcb.pdf
[4] http://www.atsdr.cdc.gov/toxprofiles/tp17-c3.pdf