Since 1999, we have been applying our unique and extensive expertise in nanofabrication, nanoelectronics, nanooptics, nanomagnetics and nanomaterials to biology for developing innovative biological manipulators, separators, detectors and analyzers for DNAs, proteins and cells. In particular, we are developing (a) new nanofabrication methods that can make smaller, larger area, better and cheaper nanobiodevices than the current technology permits, and (b) new nanobio-devices with nanofluidic channel(s), nanopillars, nano-electronic sensors and nano-optical sensors for stretching, sorting, and analyzing DNA and other bioparticles. We have been collaborating with our colleagues at Princeton, Profs. Bob Austin, Ted Cox, and Jim Sturm.
• Narrow (sub-15 nm width) and long (over 1 cm) fluidic channels
• Nano-analyzers and manipulators for DNA sequencing
• Nanopillar array for bio-material separation
• Microfluidics for blood separation and analysis
• 10 nm nanofluidic channels [APL, 81, 2002]
• Genomics in a Bottle [PNAS, 2004]
• Dynamics of DNA stretched in nanochannels [PRL, 2005