Hughson Lab Recent Publications 

1. Neiditch, M.B., Federle, M.J., Miller, S.T., Bassler, B.L., and Hughson, F.M. (2005) Regulation of LuxPQ receptor activity by the quorum sensing signal autoinducer-2.  Mol. Cell 18, 507-518.
2. Ungar, D., Oka, T., Vasile, E., Krieger, M., and Hughson, F.M. (2005) Subunit architecture of the conserved oligomeric Golgi complex. J. Biol. Chem. 280, 32729-32735.
3. Oka, T., Vasile, E., Penman, M., Novina, C.D., Dykxhoorn, D.M., Ungar, D., Hughson, F.M., Krieger, M. (2005) Genetic analysis of the subunit organization and function of the COG complex: Studies of Cog5 and Cog7 deficient mammalian cells. J. Biol. Chem. 280, 32736-32745.
4. Ungar, D., Oka, T., Krieger, M., and Hughson, F.M. (2006) Retrograde transport on the COG railway [review] Trends Cell Biol. 16, 113-120.
5. Neiditch, M.B., Federle, M.J., Pompeani, A.J., Kelly, R.C., Swem, D.L., Jeffrey, P.D., Bassler, B.L., and Hughson, F.M. (2006) Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing. Cell 126, 1095-1108.
6. Togneri, J., Cheng, Y.S., Munson, M., Hughson, F.M., and Carr, C.M. (2006) SNARE complex binding mode of the Sec1/Munc-18 protein, Sec1p. Proc. Natl. Acad. Sci. USA 103, 17730-17735.
7. Neiditch, M.B. and Hughson, F.M. (2007) The regulation of histidine sensor kinase complexes by quorum sensing signal molecules. Meth. Enzymol. 423, 250-263.
8. Cavanaugh, L.F., Chen, X., Richardson, B.C., Ungar, D., Pelczer, I., Rizo, J., and Hughson, F.M. (2007) Structural analysis of conserved oligomeric Golgi complex subunit 2.  J. Biol. Chem. 282, 23418-23426.
9. Hughson, F.M. (2008) Both layers of the COPII coat come into view [Preview]. Cell 134, 384-385.
10. Tripathi, A., Ren, Y., Jeffrey, P.D., and Hughson, F.M. (2009) Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex. Nature Struct. Molec. Biol. 16, 114-123.

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