SOFTWARE

The original codes were all developed in GNU C under Linux or Darwin platforms. While the source codes for the core analysis engines are available upon request, we are in the process of writing graphical user interface for public release. In the mean time, please direct your software requests to hawyang-at-princeton.edu.

  1. Photon-by-photon maximum-Information analysis of single-molecule FRET trajectories.
    Source code now available in Linux environment (x86_32 & x86_64).

    Please cite the following reference,
    L.P. Watkins and H. Yang, Biophys. J. 2004, 86, 4015-4029.

  2. Photon-by-photon detection of single-molecule emission intensity change points. (Corrigenda for implementation, last update 2009.08.08)
    Source code available for Linux, Darwin, and Windows MinGW command-line environments with the GNU Scientific Library. Current distribution version = 1.12 (build 20120512)

    Please cite the following reference,
    L.P. Watkins and H. Yang, J. Phys. Chem. B 2005, 109, 617-628.

  3. Detection of changes in Brownian diffusion dynamics.
    Source code available in Linux / Darwin command line environment with the GNU Scientific Library. Current distribution version = 1.11 (build 20081005).

    Please cite the following reference,
    D. Montiel, H. Cang, and H. Yang, J. Phys. Chem. B 2006, 110, 19763-19770.

Part of the software development is based upon work supported by the National Science Foundation under Grant No. CHE-0349284, by the U.S. Department of Energy under contracts No. DE-AC03-76SF00098 and KP1501021, by the Human Frontier Science Program, and by the Princeton University.

Updated: 2012.05.12.