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Mark Brynildsen

Selected Publications

For a complete listing of downloadable publications, click here.

  1. Amato SM, Orman MA, Brynildsen MP. Metabolic control of persister formation in Escherichia coli. Mol Cell, 2013 May 23; 50: 1-13.
  2. Robinson JL, Brynildsen MP. A kinetic platform to determine the fate of nitric oxide in Escherichia coli. PLoS Comp Biol, 2013 May 2; 9(5).
  3. Orman MA, Brynildsen MP. Dormancy is not necessary or sufficient for bacterial persistence. Antimicrob Agents Chemother, 2013 Apr 29 [epub ahead of print].
  4. Brynildsen MP, Winkler JA, Spina CS, MacDonald IC, Collins JJ. Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production. Nature Biotech, 2013 Feb;31(2):160-5.
  5. Allison KR, Brynildsen MP, Collins JJ. Heterogeneous bacterial persisters and engineering approaches to eliminate them, Curr Opin Microbiol. 2011 Oct;14(5):593-8.
  6. Allison KR, Brynildsen MP, Collins JJ. Metabolite-enabled eradication of bacterial persisters by aminoglycosides. Nature. 2011 May 12;473(7346):216-20.
  7. Brynildsen MP, Liao JC. An integrated network approach identifies the isobutanol response network of Escherichia coli. Mol Syst Biol, 2009; 5:277 [Epub 2009 Jun 16].
  8. Brynildsen MP, Collins JJ. Systems biology makes it personal. Mol Cell, 2009 Apr 24;34(2):137-8.
  9. Atsumi S, Cann AF, Connor MR, Shen CR, Smith KM, Brynildsen MP, Chou KJ, Hanai T, Liao JC. Metabolic engineering of Escherichia coli for 1-butanol production. Metab Eng, 2008 Nov;10(6):305-11 [Epub 2007 Sep 14].
  10. Brynildsen MP, Wu TY, Jang SS, Liao JC. Biological network mapping and source signal deduction. Bioinformatics, 2007 Jul 15;23(14):1783-91.
  11. Brynildsen MP, Tran LM, Liao JC. A Gibbs sampler for the identification of gene expression and network connectivity consistency. Bioinformatics, 2006 Dec 15;22(24):3040-6.
  12. Brynildsen MP, Tran LM, Liao JC. Versatility and connectivity efficiency of bipartite transcription networks. Biophys J, 2006 Oct 15;91(8):2749-59.
  13. Brynildsen MP, Wong WW, Liao JC. Transcriptional regulation and metabolism. Biochem Soc Trans, 2005 Dec;33(Pt 6):1423-6.
  14. Yang YL, Suen J, Brynildsen MP, Galbraith S, Liao JC. Inferring yeast cell cycle regulators and interactions using transcription factor activities. BMC Genomics, 2005 Jun 10;6(1):90.
  15. Tran LM, Brynildsen MP, Kao KC, Suen JK, Liao JC. gNCA: A framework for determining transcription factor activity based on transcriptome: Identifiability and numerical implementation. Metab Eng, 2005 Mar;7(2):128-41.