Inner workings of the brain II
Posted June 28, 2010; 10:00 a.m.
Bernd Kuhn, an associate research scholar in the laboratory of molecular biologist Sam Wang, used two-photon microscopy to make this three-dimensional reconstruction of a living mouse brain. An engineered virus was used to make the neurons express a calcium-sensitive fluorescent protein. Since calcium levels rise inside neurons when they fire, changes in brightness of the glowing cells can be used to report whether neurons are active. Read more.