Ebola

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Ivory Coast ebolavirus
Reston ebolavirus
Sudan ebolavirus

Ebola is the virus Ebolavirus (EBOV), a viral genus, and the disease Ebola hemorrhagic fever (EHF), a viral hemorrhagic fever (VHF). The virus is named after the Ebola River Valley in the Democratic Republic of the Congo (formerly Zaire), which is near the site of the first recognized outbreak in 1976 at a mission hospital run by Flemish nuns.[1] It remained largely obscure until 1989 when several widely publicized outbreaks occurred among monkeys in the United States.

The virus interferes with the endothelial cells lining the interior surface of blood vessels and with coagulation. As the blood vessel walls become damaged and destroyed, the platelets are unable to coagulate, patients succumb to hypovolemic shock. Ebola is transmitted through bodily fluids, while conjunctiva exposure may also lead to transmission.

There are five recognized species within the ebolavirus genus, which have a number of specific strains.[2] The Zaire virus is the type species, which is also the first discovered and the most lethal. Electron micrographs show long filaments, characteristic of the Filoviridae viral family.

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