Publications

Abdu, U., Brodsky, M., and Schüpbach, T. Activation of a meiotic checkpoint during Drosophila oogenesis regulates the translation of Gurken through Chk2/Mnk. (submitted to Current Biology).

Van Buskirk, C., and Schüpbach, T. (2002) Half pint regulates alternative splice site selection in Drosophila. Developmental Cell 2:343-353. | ABSTRACT | PDF

Gupta, T. and Schüpbach, T. (2001) Two signals are better than one: Border cell migration in Drosophila. Developmental Cell 1: 443-445. | ABSTRACT | PDF

Sen, J., Goltz, J.S., Konsolaki, M., Schupbach, T., and Stein, D. (2000). Windbeutel is required for function and correct subcellular localization of the Drosophila patterning protein Pipe. Development, 127, 5541-5550. | ABSTRACT | PDF

Van Buskirk, C., N. Hawkins and T. Schüpbach (2000). Encore is a member of a novel family of proteins and affects multiple processes in Drosophila oogenesis. Development, 127: 4753-4762. | ABSTRACT | PDF

Pai, L.-M., Barcelo, G., and Schüpbach, T. (2000). D-cbl, a negative regulator of the Egfr pathway, is required for dorsoventral patterning in Drosophila oogenesis. Cell,103: 51-61. | ABSTRACT | PDF

Thio, G., R. Ray, G. Barcelo and T. Schüpbach (2000). Localization of gurken in Drosophila oogenesis requires elements in the 5’ and 3’ region of the transcript. Developmental Biology 221: 435-446. | ABSTRACT | PDF

Ghabrial, A., and T. Schüpbach (1999). Activation of a meiotic checkpoint regulates translation of Gurken during Drosophila oogenesis. Nature Cell Biology 1: 354-357. | ABSTRACT | PDF

Lall, S., Francis-Lang, H., Flament, A., Norvell, A., Schüpbach, T., Ish-Horowicz, D. (1999). Squid hnRNP protein promotes apical cytoplasmic transport and localization of Drosophila pair-rule transcripts. Cell 98: 171-180.| ABSTRACT | PDF

Queenan, A.M., G. Barcelo, C. VanBuskirk, and T. Schüpbach (1999) The transmembrane region of Gurken is necessary for transport to the oocyte membrane in Drosophila. Mechanisms of Development, 89:35-42. | ABSTRACT | PDF

Norvell, A., R.L. Kelley and T. Schüpbach (1999). Specific isoforms of Squid, a Drosophila hnRNP, perform distinct roles in Gurken localization during oogenesis. Genes & Dev. 13:864-876. | ABSTRACT | PDF

VanBuskirk, C. and T. Schüpbach (1999). Versatility in signalling: multiple responses to EGF receptor activation during Drosophila oogenesis. Trends in Cell Biology 9:1-4. | ABSTRACT | PDF

Nilson, L. and T. Schüpbach (1998). EGF receptor signaling in Drosophila oogenesis. Curr. Topics Dev. Biol. 44:203-243. | ABSTRACT

Ghabrial, A., R.P. Ray and T. Schüpbach (1998). okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis. Genes & Dev. 12:2711-2723. | ABSTRACT | PDF

Nilson, L., and T. Schüpbach (1998). Localized Requirements for windbeutel and pipe Reveal a Dorsoventral Prepattern within the Follicular Epithelium of the Drosophila Ovary. Cell 93:253-262. | ABSTRACT | PDF

Schüpbach, T. and E. Wieschaus (1998). Probing for gene specificity in epithelial development. Int. J. Dev. Biol. 42:249-255. | ABSTRACT |

Konsolaki, M. and T. Schüpbach (1998). Windbeutel, a gene required for dorsoventral patterning in Drosophila, encodes a protein that has homologies to vertebrate proteins of the endoplasmic reticulum. Genes & Development 12:120-131.| ABSTRACT | PDF

Hawkins, N.C., C. VanBuskirk, U. Grossniklaus, and T. Schüpbach (1997). Posttranscriptional Regulation of gurken by encore is Required for Axis Determination in Drosophila. Development 124:4801-4810. | ABSTRACT | PDF

Queenan, A.M., A. Ghabrial, and T. Schüpbach (1997). Ectopic activation of torpedo/Egfr, a Drosophila receptor tyrosine kinase, dorsalizes both the eggshell and the embryo. Development 124:3871-3880. | ABSTRACT | PDF

Neuman-Silberberg, F. S., and T. Schüpbach (1996). The Drosophila TGF-alpha-like protein Gurken: Expression and cellular localization during Drosophila oogenesis. Mechanisms of Development 59(2):105-113. | ABSTRACT | PDF

Ray, R. P., and T. Schüpbach (1996). Intercellular signaling and the polarization of body axes during Drosophila oogenesis. Genes & Dev. 10:1711-1723. | ABSTRACT |

Hawkins, N. C., J. Thorpe, and T. Schupbach (1996). encore, a gene required for the regulation of germ line mitosis and oocyte differentiation during Drosophila oogenesis. Development 122:281-290. | ABSTRACT | PDF

Roth, S., F.S. Neuman-Silberberg, G. Barcelo, and T. Schüpbach (1995). cornichon and the EGF Receptor Signaling Process are Necessary for Both Anterior-Posterior and Dorsal-Ventral Pattern Formation in Drosophila. Cell 81:967-978. | ABSTRACT |

Schüpbach, T. and S. Roth (1994). Dorso-ventral Patterning in Drosophila oogenesis Curr. Opinion in Gen. and Dev. 4:502-507. | ABSTRACT | PDF

Neuman-Silberberg, F.S. and T. Schüpbach (1994). Dorsoventral axis formation in Drosophila depends on the correct dosage of the gene gurken. Development 120:2457-2463. | ABSTRACT | PDF

Roth, S. and T. Schüpbach (1994). The relationship between ovarian and embryonic dorso-ventral patterning in Drosophila. Development 120:2245-2257. | ABSTRACT | PDF

Clifford, R. and T. Schüpbach (1994). Molecular analysis of the Drosophila EGF receptor homolog reveals that several genetically defined classes of alleles cluster in subdomains of the receptor protein. Genetics 137:531-550. | ABSTRACT

Neuman-Silberberg, F.S. and T. Schüpbach (1993). The Drosophila dorso-ventral patterning gene gurken produces a dorsally localized RNA and encodes a TGF-alpha like protein. Cell 75:165-174. | ABSTRACT| PDF

Clifford, R. and T. Schüpbach (1992). The torpedo (DER) receptor tyrosive kinase is required at multiple times during Drosophila oogenesis. Development 115:853-872. | ABSTRACT

Schüpbach, T. and E. Wieschaus (1991). Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology. Genetics 129:1119-1136. | ABSTRACT

Schüpbach, T., R.J. Clifford, L.J. Manseau and J.V. Price (1990). Dorso-ventral signalling processes in Drosophila oogenesis. In: Cell-Cell Interactions in Early Development. 49th Symp. Soc. Devel. Biol., ed. J. Gerhart, Wiley-Liss Inc., New York. pp. 163-174.

Manseau, L. J. and T. Schüpbach (1989). The egg came first, of course! Anterior-posterior pattern formation in Drosophila embryogenesis and oogenesis. TIGS 5: 400-405. | ABSTRACT

Clifford, R. J. and T. Schüpbach (1989). Coordinately and differentially mutable activities of torpedo, the Drosophila melanogaster homolog of the vertebrate EGF receptor gene. Genetics 123:771-787. | ABSTRACT

Manseau, L. J. and T. Schüpbach (1989). cappucino and spire: Two unique maternal effect loci that are required for both the anterior-posterior and dorso-ventral patterns of the Drosophila embryo. Genes & Dev. 3:1437-1452. | ABSTRACT

Price, J. V., R. J. Clifford and T. Schüpbach (1989). The maternal ventralizing locus torpedo is allelic to faint little ball, an embryonic lethal, and encodes the Drosophila EGF receptor homolog. Cell 56:1085-1092. | ABSTRACT

Schüpbach, T. and E. Wieschaus (1989). Female sterile mutations on the second chromosome of Drosophila melanogaster. I. Maternal effect mutations. Genetics 121: 101-117. | ABSTRACT

Schüpbach, T. (1987). Germline and soma cooperate during oogenesis to establish the dorso-ventral pattern of egg shell and embryo in Drosophila melanogaster. Cell 49:699-707.

Steward, R., L. Ambrosio and T. Schüpbach (1986). Polarity in the Oocyte and Embryo of Drosophila. In: Molecular Approaches to Developmental Biology (UCLA Symposia on Molecular and Cell Biology, New Series, R. A. Firtel and E. H. Davidson, eds.). Alan R. Liss, Inc., New York. 51:39-50.

Carroll, S. B., G. M. Winslow, T. Schüpbach and M. P. Scott (1986). Maternal control of Drosophila segmentation gene expression. Nature 323:278-280.

Schüpbach, T. and E. Wieschaus (1986). Maternal-effect mutations altering the anterior-posterior pattern of the Drosophila embryo. Roux's Arch. Dev. Biol. 195:302-317.

Schüpbach, T. and E. Wieschaus (1986). Germline autonomy of maternal-effect mutations altering the embryonic body pattern of Drosophila. Dev. Biol. 113:443-448.

Schüpbach, T. (1985). Normal female germ cell differentiation requires the female X-chromosome-autosome ratio and expression of Sex-lethal in Drosophila melanogaster. Genetics 109:529-548.

Schüpbach, T. (1982). Autosomal mutations that interfere with sex determination in somatic cells of Drosophila have no direct effect on the germline. Dev. Biol. 89:117-127.

Nöthiger, R., M. Roost and T. Schüpbach (1980). Masculinizer is an allele of double sex. Drosophila Information Service 55:118.

Szabad, J., T. Schüpbach and E. Wieschaus (1979). Cell lineage and development in the larval epidermis of Drosophila melanogaster. Dev. Biol. 73:256-271.

Schüpbach, T., E. Wieschaus and R. Nöthiger (1978). The embryonic organization of the genital disc studies in genetic mosaics of Drosophila melanogaster. Roux's Arch. Dev. Biol. 185:249-270.

Nöthiger, R., T. Schüpbach, J. Szabad and E. Wieschaus (1978). Stem cells and tissue homeostasis in insect development. In: Stem Cells and Tissue Homeostasis (British Society for Cell Biology Symposium 2, Lord, Potten, Cole, eds.). Cambridge University Press, Cambridge-London-New York-Melbourne.

Schüpbach, T., E. Wieschaus and R. Nöthiger (1978). A study of the female germline in mosaics of Drosophila. Roux's Arch. Dev. Biol. 184:41-56.